Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29521733 | 0.91 | KMT2A (0.59) | KMT2AFABP5CD274EPHX2CASP3 | |
| SCHEMBL348791 | 0.91 | KMT2A (0.59) | KMT2AFABP5CD274EPHX2CASP3 | |
| SCHEMBL30340748 | 0.91 | KMT2A (0.59) | KMT2AFABP5CD274EPHX2CASP3 | |
| SCHEMBL3127362 | 0.85 | KMT2A (0.55) | KMT2AFABP5EPHX2CASP3 | |
| SCHEMBL14438907 | 0.83 | KMT2A (0.48) | KMT2AFABP5CD274EPHX2 | |
| SCHEMBL8013815 | 0.83 | KMT2A (0.69) | KMT2AS1PR1 | |
| SCHEMBL11888362 | 0.82 | KMT2A (0.47) | KMT2AFABP5CD274EPHX2 | |
| SCHEMBL1290287 | 0.82 | KMT2A (0.52) | KMT2AFABP5CASP3 | |
| SCHEMBL7166142 | 0.81 | KMT2A (0.45) | KMT2AFABP5CD274LMNA | |
| SCHEMBL118248 | 0.80 | KMT2A (0.62) | KMT2AFABP5EPHX2CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130330369-A1 | Reduction Of Antibody Response Against Botulinum Neurotoxin And Variants Thereof | ALLERGAN, INC. (US) | 2013-12-12 | — | — | US | disclosed |
| WO-2012048246-A1 | REDUCTION OF ANTIBODY RESPONSE AGAINST BOTULINUM NEUROTOXIN AND VARIANTS THEREOF | ALLERGAN, INC. (US) | 2012-04-12 | — | — | WO | disclosed |