SCHEMBL29521733

SCHEMBL29521733

COc1cc(OCCCCC(=O)O)cc(OC)c1CNC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.59

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 2/20 0.59
▸ FABP5 Q01469 1/20 0.42
▸ PTPN1 P18031 1/20 0.42
▸ CD274 Q9NZQ7 5/20 0.41
▸ EPHX2 P34913 1/20 0.40
▸ CASP3 P42574 1/20 0.39
▸ HDAC1 Q13547 2/20 0.39
▸ HDAC6 Q9UBN7 2/20 0.39
▸ HDAC3 O15379 1/20 0.39
▸ PDCD1 Q15116 1/20 0.39
▸ HDAC2 Q92769 1/20 0.39
▸ HDAC8 Q9BY41 1/20 0.39
▸ TLR2 O60603 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30340748 1.00 KMT2A (0.59) KMT2AFABP5PTPN1CD274EPHX2
SCHEMBL348791 1.00 KMT2A (0.59) KMT2AFABP5PTPN1CD274EPHX2
SCHEMBL14438907 0.93 KMT2A (0.48) KMT2AFABP5PTPN1CD274EPHX2
SCHEMBL1290289 0.91 KMT2A (0.62) KMT2AFABP5CD274EPHX2CASP3
SCHEMBL11888362 0.91 KMT2A (0.47) KMT2AFABP5PTPN1CD274EPHX2
SCHEMBL14891353 0.88 KMT2A (0.43) KMT2AFABP5PTPN1CD274EPHX2
SCHEMBL118248 0.88 KMT2A (0.62) KMT2AFABP5PTPN1EPHX2CASP3
SCHEMBL15521041 0.87 KMT2A (0.45) KMT2AFABP5PTPN1CD274EPHX2
SCHEMBL3127362 0.87 KMT2A (0.55) KMT2AFABP5PTPN1EPHX2CASP3
SCHEMBL12638185 0.84 KMT2A (0.44) KMT2AFABP5PTPN1CD274EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4311832-A1 PHOTOCAGED OREXIN-B Universität Zürich (CH) 2024-01-31 — — EP claimed
CN-114230633-B Polypeptide capable of repairing oxidative stress injury and preparation method and application thereof 浙江湃肽生物股份有限公司 2023-05-30 — — CN claimed
US-12612619-B2 Compositions and methods for improved gene editing UNIVERSITY OF MASSACHUSETTS (US) 2026-04-28 — — US disclosed
US-12565506-B2 Nitrogen-containing macrocyclic conjugates as radiopharmaceuticals Clarity Pharmaceuticals Ltd (AU) 2026-03-03 — — US disclosed
EP-3727435-B1 BIVALENT NUCLEIC ACID LIGANDS AND USES THEREFOR UNIV CARNEGIE MELLON (US) 2026-02-18 — — EP disclosed
US-12551535-B2 Peptide pharmaceuticals for insulin resistance MEDERIS DIABETES, LLC (US) 2026-02-17 — — US disclosed
EP-4683911-A1 NOVEL TAG FOR LIQUID-PHASE PEPTIDE SYNTHESIS CordenPharma International GmbH (DE) 2026-01-28 — — EP disclosed
US-20250369027-A1 SUBSTRATE CLEAVAGE FOR NUCLEIC ACID SYNTHESIS TWIST BIOSCIENCE CORP (US) 2025-12-04 — — US disclosed
EP-4640701-A2 GLUCAGON LIKE PEPTIDE 1 (GLP-1) FUSION PEPTIDE COUPLED CYCLIC PEPTIDE TYROSINE TYROSINE CONJUGATES AND USES THEREOF Janssen Sciences Ireland Unlimited Company (IE) 2025-10-29 — — EP disclosed
EP-4638480-A1 AMYLIN RECEPTOR AGONISTS Novo Nordisk A/S (DK) 2025-10-29 — — EP disclosed
US-20250313604-A1 PEPTIDE PHARMACEUTICALS FOR INSULIN RESISTANCE MEDERIS DIABETES LLC (US) 2025-10-09 — — US disclosed
CN-108712913-B Tri-part modulators of endosomal G protein-coupled receptors 武田药品工业株式会社 2022-06-24 — — CN disclosed
US-11332495-B2 Process for the preparation of Degarelix acetate and Degarelix acetate-mannitol premix RK Pharma Solutions LLC (US) 2022-05-17 — — US disclosed
WO-2022096736-A1 COMPOUNDS AND THEIR USE IN TREATMENT OF TACHYKININ RECEPTOR MEDIATED DISORDERS EMBARK BIOTECH APS (DK) 2022-05-12 — — WO disclosed
EP-3993820-A1 ANTIBODIES TO HUMAN PROGRAMMED DEATH RECEPTOR PD-1 Cadila Healthcare Limited (IN) 2022-05-11 — — EP disclosed
US-11324832-B2 Tripartite modulators of endosomal G protein-coupled receptors ENDOSOME THERAPEUTICS, INC. (US) 2022-05-10 — — US disclosed
US-11325945-B2 Peptide based PCSK9 vaccine CADILA HEALTHCARE LIMITED (IN) 2022-05-10 — — US disclosed
US-11319343-B2 Method of treatment ROYAL MELBOURNE INSTITUTE OF TECHNOLOGY (AU) 2022-05-03 — — US disclosed
EP-3987024-A1 COMPOSITIONS AND METHODS FOR IMPROVED GENE EDITING University Of Massachusetts (US) 2022-04-27 — — EP disclosed
EP-3988123-A1 ANTIBODY-COUPLED CYCLIC PEPTIDE TYROSINE TYROSINE COMPOUNDS AS MODULATORS OF NEUROPEPTIDE Y RECEPTORS Janssen Pharmaceutica NV (BE) 2022-04-27 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12565506-B2 Nitrogen-containing macrocyclic conjugates as radiopharmaceuticals CA12, CLTC, CA13 KMT2A 2695/4885FABP5 3555/4885PTPN1 2231/4885
US-11325945-B2 Peptide based PCSK9 vaccine PCSK9, PCSK7, PCSK6 KMT2A 2907/4885FABP5 516/4885PTPN1 1577/4885
US-12551535-B2 Peptide pharmaceuticals for insulin resistance IAPP, GLP1R, INSR KMT2A 2881/4885FABP5 94/4885PTPN1 1989/4885
US-11324832-B2 Tripartite modulators of endosomal G protein-coupled receptors NTSR1, NTSR2, MRGPRX2 KMT2A 2755/4885FABP5 2424/4885PTPN1 2372/4885
US-11332495-B2 Process for the preparation of Degarelix acetate and Degarelix acetate-mannitol premix PEPD, DNPEP, PREP KMT2A 2862/4885FABP5 4499/4885PTPN1 4741/4885
US-12612619-B2 Compositions and methods for improved gene editing ALKBH2, ALKBH1, ALKBH3 KMT2A 582/4885FABP5 2689/4885PTPN1 3749/4885
US-20250313604-A1 PEPTIDE PHARMACEUTICALS FOR INSULIN RESISTANCE IAPP, GLP1R, PTMS KMT2A 4134/4885FABP5 105/4885PTPN1 1516/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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