SCHEMBL1290744

SCHEMBL1290744

CCCCCCCCNC(=O)C=CC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.64
ZDHHC2 Q9UIJ5 2/20 0.60
NAAA Q02083 4/20 0.52
EPHX1 P07099 3/20 0.50
ALDH1A1 P00352 1/20 0.50
HTT P42858 1/20 0.50
ZDHHC20 Q5W0Z9 1/20 0.50
HDAC3 O15379 2/20 0.48
HDAC4 P56524 2/20 0.48
HDAC1 Q13547 2/20 0.48
HDAC7 Q8WUI4 2/20 0.48
HDAC2 Q92769 2/20 0.48
HDAC10 Q969S8 2/20 0.48
HDAC11 Q96DB2 2/20 0.48
HDAC8 Q9BY41 2/20 0.48
HDAC6 Q9UBN7 2/20 0.48
HDAC9 Q9UKV0 2/20 0.48
HDAC5 Q9UQL6 2/20 0.48
APP P05067 1/20 0.47
KMT2A Q03164 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1291063 1.00 EGFR (0.64) EGFRZDHHC2NAAAEPHX1ALDH1A1
SCHEMBL1291118 0.94 EGFR (0.56) EGFRZDHHC2NAAAEPHX1ALDH1A1
N-Hexadecylcinnamamide SCHEMBL2727701 0.78 EGFR (1.00) EGFRZDHHC2HDAC3HDAC4HDAC1
N-Octylcinnamamide SCHEMBL10706126 0.78 EGFR (1.00) EGFRZDHHC2HDAC3HDAC4HDAC1
N-Dodecylcinnamamide SCHEMBL16596238 0.78 EGFR (1.00) EGFRZDHHC2HDAC3HDAC4HDAC1
N-Dodecylcinnamamide SCHEMBL28975087 0.78 EGFR (1.00) EGFRZDHHC2HDAC3HDAC4HDAC1
SCHEMBL28975079 0.78 EGFR (1.00) EGFRZDHHC2HDAC3HDAC4HDAC1
SCHEMBL6726303 0.78 EGFR (0.73) EGFRZDHHC2NAAAEPHX1ALDH1A1
SCHEMBL5485829 0.78 EGFR (0.73) EGFRZDHHC2NAAAEPHX1ALDH1A1
N-Pentylcinnamamide SCHEMBL7913716 0.77 EGFR (0.97) EGFRZDHHC2HDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1173878-B1 PROBES FOR A GAS PHASE ION SPECTROMETER BIO RAD LABORATORIES (US) 2011-04-06 EP claimed
US-7205156-B2 Probes for a gas phase ion spectrometer BIO-RAD LABORATORIES, INC. (US) 2007-04-17 US claimed
US-6897072-B1 Probes for a gas phase ion spectrometer CIPHERGEN BIOSYSTEMS, INC. (US) 2005-05-24 US claimed
US-10736989-B2 Methods and compositions for stabilizing the myocardium THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2020-08-11 US disclosed
US-20170119925-A1 METHODS AND COMPOSITIONS FOR STABILIZING THE MYOCARDIUM THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2017-05-04 US disclosed
US-9480807-B2 Device and method for detection and treatment of ventilator associated pneumonia in a mammalian subject ELWHA LLC (US) 2016-11-01 US disclosed
US-9415135-B2 Methods and compositions for stabilizing the myocardium THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2016-08-16 US disclosed
US-20150090269-A1 Device and Method for Detection and Treatment of Ventilator Associated Pneumonia in a Mammalian Subject ELWHA LLC 2015-04-02 US disclosed
US-20150090263-A1 Device and Method for Detection and Treatment of Ventilator Associated Pneumonia in a Mammalian Subject ELWHA LLC 2015-04-02 US disclosed
US-20150090270-A1 Device and Method for Detection and Treatment of Ventilator Associated Pneumonia in a Mammalian Subject ELWHA LLC 2015-04-02 US disclosed
US-20130281602-A1 Thermo-responsive polymer covalently bound with a peptide SOLVAY SA (BE) 2013-10-24 US disclosed
EP-1451554-A1 HYDROPHOBIC SURFACE CHIP Ciphergen Biosystems, Inc. (US) 2004-09-01 EP disclosed
US-20040001892-A1 Tunable, semi-interpenetrating polymer networks (sIPNS) for medicine and biotechnology THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2004-01-01 US disclosed
US-20030218130-A1 Biochips with surfaces coated with polysaccharide-based hydrogels CIPHERGEN BIOSYSTEMS, INC. 2003-11-27 US disclosed
WO-2003093785-A2 BIOCHIPS WITH SURFACES COATED WITH POLYSACCHARIDE BASED HYDROGELS CIPHERGEN BIOSYSTEMS, INC. (US) 2003-11-13 WO disclosed
US-20030124371-A1 Hydrophobic surface chip CIPHERGEN BIOSYSTEMS, INC. 2003-07-03 US disclosed
WO-2003040700-A1 HYDROPHOBIC SURFACE CHIP CIPHERGEN BIOSYSTEMS, INC. (US) 2003-05-15 WO disclosed
EP-1173878-A2 PROBES FOR A GAS PHASE ION SPECTROMETER Ciphergen Biosystems, Inc. (US) 2002-01-23 EP disclosed
WO-2000066265-A9 PROBES FOR A GAS PHASE ION SPECTROMETER CIPHERGEN BIOSYSTEMS INC (US) 2001-09-07 WO disclosed
WO-2000066265-A2 PROBES FOR A GAS PHASE ION SPECTROMETER CIPHERGEN BIOSYSTEMS, INC. (US) 2000-11-09 WO disclosed