N-Pentylcinnamamide

N-Pentylcinnamamide

SCHEMBL7913716

CCCCCNC(=O)/C=C/c1ccccc1

nearest known ligand 0.97

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.97
KMT2A Q03164 1/20 0.79
HDAC3 O15379 4/20 0.68
HDAC1 Q13547 3/20 0.68
HDAC2 Q92769 3/20 0.68
HDAC4 P56524 1/20 0.68
HDAC7 Q8WUI4 1/20 0.68
HDAC10 Q969S8 1/20 0.68
HDAC11 Q96DB2 1/20 0.68
HDAC8 Q9BY41 1/20 0.68
HDAC6 Q9UBN7 1/20 0.68
HDAC9 Q9UKV0 1/20 0.68
HDAC5 Q9UQL6 1/20 0.68
APP P05067 1/20 0.66
MMP1 P03956 2/20 0.63
MMP2 P08253 2/20 0.63
MMP9 P14780 2/20 0.63
POLB P06746 1/20 0.63
RECQL P46063 1/20 0.63
ZDHHC2 Q9UIJ5 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
N-Pentylcinnamamide SCHEMBL7913718 1.00 EGFR (0.97) EGFRKMT2AHDAC3HDAC1HDAC2
N-Octylcinnamamide SCHEMBL10706126 0.98 EGFR (1.00) EGFRKMT2AHDAC3HDAC1HDAC2
N-Dodecylcinnamamide SCHEMBL28975087 0.98 EGFR (1.00) EGFRKMT2AHDAC3HDAC1HDAC2
SCHEMBL28975079 0.98 EGFR (1.00) EGFRKMT2AHDAC3HDAC1HDAC2
N-Hexadecylcinnamamide SCHEMBL2727701 0.98 EGFR (1.00) EGFRKMT2AHDAC3HDAC1HDAC2
N-Dodecylcinnamamide SCHEMBL16596238 0.98 EGFR (1.00) EGFRKMT2AHDAC3HDAC1HDAC2
N-Butylcinnamamide SCHEMBL6231267 0.95 EGFR (0.88) EGFRKMT2AHDAC3HDAC1HDAC2
N-Butylcinnamamide SCHEMBL3688039 0.95 EGFR (0.88) EGFRKMT2AHDAC3HDAC1HDAC2
SCHEMBL3208177 0.92 KMT2A (0.93) EGFRKMT2AHDAC3HDAC1HDAC2
SCHEMBL28975041 0.92 EGFR (0.87) EGFRKMT2AHDAC3HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7320993-B1 Aryl-substituted pyridylalkane, alkene, and alkine carboxamides useful as cytostatic useful as cytostatic and immuosuppressive agents ASTELLAS DEUTSCHLAND GMBH (DE) 2008-01-22 US disclosed
US-6215001-B1 ANTIINFLAMMATORY AGENTS, ANTIASTHMATICS, AND ANTIALLERGENS; SIDE EFFECT REDUCTION KNOLL AKTIENGESELLSCHAFT (DE) 2001-04-10 US disclosed