Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 5/20 | 0.71 |
| ▸ | BCR | P11274 | 4/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.60 |
| ▸ | TNNI3K | Q59H18 | 5/20 | 0.57 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.54 |
| ▸ | CDK9 | P50750 | 3/20 | 0.54 |
| ▸ | BACE1 | P56817 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12907759 | 0.91 | ABL1 (0.60) | ABL1BCRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL12907758 | 0.87 | ABL1 (0.59) | ABL1BCRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3899953 | 0.83 | ABL1 (1.00) | ABL1BCRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL12907698 | 0.83 | CYP2D6 (0.55) | ABL1BCRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4117487 | 0.81 | CCNT1 (0.67) | ABL1BCRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL12907690 | 0.80 | TP53 (0.64) | ABL1BCRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL12907662 | 0.79 | ABL1 (0.71) | ABL1BCRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4664257 | 0.79 | CCNT1 (0.64) | ABL1BCRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4665854 | 0.79 | BACE1 (0.60) | ABL1BCRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL12907711 | 0.78 | ABL1 (0.69) | ABL1BCRCYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110021524-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCERS | IRM LLC (BM) | 2011-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021524-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCERS | ABL1, BCR, MCL1 | ABL1 1/4885BCR 2/4885CYP1A2 3945/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.