Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL924039 | 0.89 | KDM4E (0.38) | KDM4EALDH1A1GAA | |
| SCHEMBL924038 | 0.89 | KDM4E (0.38) | KDM4EALDH1A1GAA | |
| SCHEMBL12907807 | 0.84 | PRF1 (0.33) | KDM4EALDH1A1GAA | |
| SCHEMBL12907827 | 0.79 | ADORA1 (0.58) | — | |
| SCHEMBL12907805 | 0.78 | MAPK8 (0.38) | KDM4EALDH1A1GAA | |
| SCHEMBL12534760 | 0.78 | ADORA1 (0.38) | KDM4EALDH1A1 | |
| SCHEMBL12907810 | 0.77 | NPY1R (0.34) | KDM4EALDH1A1GAA | |
| SCHEMBL12907809 | 0.77 | NPY1R (0.37) | KDM4EALDH1A1GAA | |
| SCHEMBL12907806 | 0.77 | NPY1R (0.34) | KDM4EALDH1A1GAA | |
| SCHEMBL12534753 | 0.77 | ADORA1 (0.44) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110021487-A1 | CYCLOALKOXY-SUBSTITUTED 4-PHENYL-3,5-DICYANOPYRIDINES AND THEIR USE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021487-A1 | CYCLOALKOXY-SUBSTITUTED 4-PHENYL-3,5-DICYANOPYRIDINES AND THEIR USE | PC, DPP4, FABP3 | KDM4E 1690/4885ALDH1A1 1899/4885GAA 510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.