SCHEMBL12908006

SCHEMBL12908006

Cc1cccc(Oc2ccc(N3C(=O)c4ccc(Oc5ccc6c(c5)C(=O)N(c5cccc(-c7cccc(-c8cccc(N9C(=O)c%10ccc(C#Cc%11ccccc%11)cc%10C9=O)c8)c7)c5)C6=O)cc4C3=O)cc2)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.49
KMT2A Q03164 7/20 0.49
BRD4 O60885 1/20 0.47
ALDH1A1 P00352 6/20 0.44
MAPT P10636 2/20 0.44
MAPK1 P28482 2/20 0.44
POLB P06746 1/20 0.44
MCHR1 Q99705 1/20 0.43
HTT P42858 1/20 0.43
LPAR1 Q92633 1/20 0.41
LPAR5 Q9H1C0 1/20 0.41
LPAR3 Q9UBY5 1/20 0.41
GAA P10253 1/20 0.39
HPGD P15428 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HPSE Q9Y251 1/20 0.39
NPSR1 Q6W5P4 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
FFAR1 O14842 1/20 0.38
PKM P14618 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12908009 1.00 MEN1 (0.49) MEN1KMT2ABRD4ALDH1A1MAPT
SCHEMBL19689371 0.89 BRD4 (0.58) MEN1KMT2ABRD4ALDH1A1MAPT
SCHEMBL6400602 0.88 BRD4 (0.56) MEN1KMT2ABRD4ALDH1A1MAPT
SCHEMBL12908010 0.87 MEN1 (0.47) MEN1KMT2ABRD4ALDH1A1MAPT
SCHEMBL12908007 0.87 MEN1 (0.47) MEN1KMT2ABRD4ALDH1A1MAPT
SCHEMBL10000443 0.87 MEN1 (0.56) MEN1KMT2ABRD4ALDH1A1MAPT
SCHEMBL84247 0.87 MEN1 (0.58) MEN1KMT2ABRD4ALDH1A1MAPT
SCHEMBL15695540 0.85 BRD4 (0.56) MEN1KMT2ABRD4ALDH1A1MAPT
SCHEMBL14259658 0.83 MEN1 (0.50) MEN1KMT2ABRD4ALDH1A1MAPT
SCHEMBL12943325 0.83 MEN1 (0.35) MEN1KMT2ABRD4ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110003955-A1 Imide Oligomer And Polyimide Resin Obtained By Thermal Curing Thereof DAIWA CAN COMPANY (JP) 2011-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110003955-A1 Imide Oligomer And Polyimide Resin Obtained By Thermal Curing Thereof PUF60, SMARCC2, SMARCA4 MEN1 888/4885KMT2A 878/4885BRD4 509/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.