Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.50 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.50 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 4/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19689371 | 0.99 | BRD4 (0.58) | BRD4MEN1KMT2APOLBMAPK1 | |
| SCHEMBL15695540 | 0.94 | BRD4 (0.56) | BRD4MEN1KMT2APOLBMAPK1 | |
| SCHEMBL84247 | 0.92 | MEN1 (0.58) | BRD4MEN1KMT2APOLBMAPK1 | |
| SCHEMBL10000448 | 0.91 | BRD4 (0.55) | BRD4MEN1KMT2APOLBMAPK1 | |
| SCHEMBL10000443 | 0.90 | MEN1 (0.56) | BRD4MEN1KMT2APOLBMAPK1 | |
| SCHEMBL29308141 | 0.89 | BRD4 (0.56) | BRD4MEN1KMT2APOLBMAPK1 | |
| SCHEMBL12908006 | 0.88 | MEN1 (0.49) | BRD4MEN1KMT2APOLBMAPK1 | |
| SCHEMBL12908009 | 0.88 | MEN1 (0.49) | BRD4MEN1KMT2APOLBMAPK1 | |
| SCHEMBL13023415 | 0.87 | MEN1 (0.57) | BRD4MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL14259658 | 0.86 | MEN1 (0.50) | BRD4MEN1KMT2APOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6911519-B2 | For use as films, melt coatings, adhesives, matrix and RTM resins; protective coatings of optical fibers | UNIVERSITY OF CONNECTICUT (US) | 2005-06-28 | — | — | US | claimed |
| US-20040006196-A1 | Low viscosity melt processable high temperature polyimides | UNIVERSITY OF CONNECTICUT | 2004-01-08 | — | — | US | claimed |
| US-6395907-B1 | Preparation of polyaromatic-ethynyl thermal setting agents | VIRGINIA COMMONWEALTH UNIVERSITY | 2002-05-28 | — | — | US | disclosed |