Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.46 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.45 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | BCL6 | P41182 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3126236 | 0.84 | KDM1A (0.47) | KDM1AKCNQ3KCNQ2FFAR1L3MBTL1 | |
| SCHEMBL1239663 | 0.84 | BCL6 (0.45) | TUBB1BCL6MAPT | |
| SCHEMBL29463708 | 0.83 | F2 (0.47) | L3MBTL1RORCTDP1ALDH1A1MAPT | |
| SCHEMBL28150355 | 0.83 | F2 (0.47) | L3MBTL1RORCTDP1ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL3113589 | 0.82 | KDM1A (0.46) | KDM1AKCNQ3KCNQ2FFAR1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL14999711 | 0.82 | BCL6 (0.44) | TUBB1BCL6MAPT | |
| SCHEMBL23409020 | 0.79 | EPHX2 (0.58) | — | |
| SCHEMBL1223575 | 0.79 | KDM4E (0.53) | L3MBTL1ALDH1A1MAPTKDM4E | |
| SCHEMBL5506635 | 0.79 | MAPT (0.54) | ALDH1A1MAPTKDM4E | |
| SCHEMBL9806039 | 0.79 | MAPT (0.43) | L3MBTL1RORCTDP1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697347-B1 | 5- OR 6-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION | TIBOTEC PHARM LTD (IE) | 2011-02-23 | — | — | EP | disclosed |