Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | F7 | P08709 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 9/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | THRB | P10828 | 3/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28150355 | 1.00 | F2 (0.47) | F2F10PRSS1F7MAPT | |
| SCHEMBL5506635 | 0.91 | MAPT (0.54) | MAPTKDM4EALDH1A1GAAHSD17B10 | |
| SCHEMBL1223575 | 0.91 | KDM4E (0.53) | F2F10PRSS1F7MAPT | |
| SCHEMBL9806039 | 0.83 | MAPT (0.43) | F2F10PRSS1F7MAPT | |
| SCHEMBL12909142 | 0.83 | KDM1A (0.46) | MAPTKDM4EALDH1A1TDP1RORC | |
| SCHEMBL9570453 | 0.82 | ALDH1A1 (0.53) | MAPTKDM4EALDH1A1GAAHSD17B10 | |
| SCHEMBL12215337 | 0.82 | PDE4A (0.47) | F2F10PRSS1F7MAPT | |
| SCHEMBL10931733 | 0.80 | F2 (0.47) | F2F10PRSS1F7MAPT | |
| SCHEMBL9877493 | 0.79 | TDP1 (0.38) | F2F10PRSS1F7MAPT | |
| SCHEMBL2890250 | 0.79 | TDP1 (0.37) | F2F10PRSS1F7MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111170847-B | Novel method for preparing drotaverine hydrochloride intermediate | 江苏联环药业股份有限公司 | 2022-02-18 | — | — | CN | disclosed |