Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10149829 | 0.83 | ROCK1 (0.60) | GPR84ROCK1NR3C1PARP1MAPT | |
| SCHEMBL7241763 | 0.72 | MAPT (0.60) | SLC6A2SLC6A4MAPTHTTSMN1; SMN2 | |
| SCHEMBL10149845 | 0.68 | ROCK1 (0.56) | ROCK1MAPTHTTSMN1; SMN2GAA | |
| SCHEMBL18280142 | 0.68 | SLC6A2 (0.54) | SLC6A2SLC6A4MAPTHTTSMN1; SMN2 | |
| SCHEMBL10149810 | 0.67 | GAA (0.60) | ROCK1MAPTHTTSMN1; SMN2GAA | |
| SCHEMBL1657138 | 0.67 | ROCK2 (0.58) | ROCK1MAPTGAATSHRALDH1A1 | |
| SCHEMBL1659090 | 0.66 | KDM4E (0.55) | ROCK1PARP1MAPTGAATSHR | |
| SCHEMBL5378650 | 0.65 | F2 (0.53) | SLC6A4MAPTHTTSMN1; SMN2GFER | |
| SCHEMBL1657432 | 0.64 | KDM4E (0.52) | ROCK1PARP1MAPTGAATSHR | |
| SCHEMBL12909290 | 0.63 | POLB (0.65) | ROCK1MAPTHTTSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011019400-A2 | ENHANCEMENT OF CELLULAR TRANSPLANTATION USING SMALL MOLECULE MODULATORS HEPATOCYTE GROWTH FACTOR (SCATTER FACTOR) ACTIVITY | ANGION BIOMEDICA CORP. (US) | 2011-02-17 | — | — | WO | disclosed |