Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL130136 | 0.85 | POLB (0.51) | POLBLMNAMAPTNPSR1BACE1 | |
| SCHEMBL12305419 | 0.84 | BACE1 (0.49) | POLBLMNAMAPTNPSR1BACE1 | |
| SCHEMBL12895598 | 0.79 | NQO1 (0.48) | POLBLMNAMAPTNPSR1BACE1 | |
| SCHEMBL13093357 | 0.78 | ADRB3 (0.51) | CASRPOLBMAPTHTTKMT2A | |
| SCHEMBL12895597 | 0.78 | LMNA (0.53) | POLBLMNAMAPTNPSR1BACE1 | |
| SCHEMBL4045324 | 0.78 | BACE1 (0.58) | POLBLMNAMAPTBACE1HTT | |
| SCHEMBL10031081 | 0.77 | CASR (0.40) | CASRLMNABACE1HTTHIF1A | |
| SCHEMBL19001619 | 0.77 | AR (0.52) | POLBLMNAMAPTNPSR1BACE1 | |
| SCHEMBL20244212 | 0.76 | CASR (0.38) | CASRMAPTBACE1HIF1AKMT2A | |
| SCHEMBL12134359 | 0.76 | NQO1 (0.52) | POLBLMNAMAPTNPSR1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8703264-B2 | Optical disc | DIC CORPORATION (JP) | 2014-04-22 | — | — | US | disclosed |
| US-20120060175-A1 | OPTICAL DISC | DIC CORPORATION (JP) | 2012-03-08 | — | — | US | disclosed |