SCHEMBL12911644

SCHEMBL12911644

CC(=O)NNC(=O)c1cccc(Cl)c1NC(=O)c1cc(Br)nn1-c1ncccc1Cl

nearest known ligand 0.62

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 3/20 0.45
MALT1 Q9UDY8 2/20 0.33
ALDH1A1 P00352 2/20 0.33
F10 P00742 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
GAA P10253 1/20 0.33
GFER P55789 1/20 0.33
KDR P35968 1/20 0.33
POLB P06746 1/20 0.33
TYK2 P29597 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12911684 0.94 DHODH (0.44) DHODHMALT1MEN1KMT2AGAA
SCHEMBL12911683 0.94 DHODH (0.49) DHODHMALT1SMN1; SMN2
SCHEMBL12911713 0.92 DHODH (0.42) DHODHMALT1ALDH1A1MEN1KMT2A
SCHEMBL12911663 0.91 DHODH (0.51) DHODHMALT1F10MEN1KMT2A
SCHEMBL12911723 0.91 DHODH (0.41) DHODHMALT1MEN1KMT2AGAA
SCHEMBL13072490 0.91 DHODH (0.46) DHODHMALT1ALDH1A1MEN1KMT2A
SCHEMBL12911664 0.90 DHODH (0.43) DHODHMALT1TYK2
SCHEMBL12911708 0.90 DHODH (0.43) DHODHALDH1A1
SCHEMBL12911673 0.90 DHODH (0.42) DHODHMALT1MEN1KMT2AGAA
SCHEMBL12527831 0.89 DHODH (0.40) DHODHMALT1ALDH1A1GAATYK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7867949-B2 Hydrazide compound and pesticidal use of the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-11 US disclosed
US-20090181956-A1 Hydrazide Compound and Pesticidal Use of the Same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-07-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090181956-A1 Hydrazide Compound and Pesticidal Use of the Same ACHE, DDT, CAT DHODH 284/4885MALT1 4865/4885ALDH1A1 436/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.