Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | FLT3 | P36888 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | BMX | P51813 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.33 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12912482 | 0.85 | MAPK1 (0.51) | MAPTKDM4EALDH1A1FLT3MAPK1 | |
| SCHEMBL12912438 | 0.83 | PDE10A (0.41) | MAPTKDM4EALDH1A1HPGDFLT3 | |
| SCHEMBL12912447 | 0.83 | CRBN (0.44) | CNR2MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL12912484 | 0.82 | CNR2 (0.41) | CNR2MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL12912449 | 0.81 | CNR2 (0.40) | CNR2MAPTALDH1A1HPGDFLT3 | |
| SCHEMBL12912477 | 0.79 | CNR2 (0.41) | CNR2MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL14499562 | 0.77 | CNR2 (0.40) | CNR2ALDH1A1MAPK1HTTADORA2A | |
| SCHEMBL9611731 | 0.76 | MAPK1 (0.54) | MAPTKDM4EALDH1A1FLT3MAPK1 | |
| SCHEMBL20286689 | 0.76 | MAPK1 (0.50) | CNR2KDM4EALDH1A1HPGDMAPK1 | |
| SCHEMBL23251179 | 0.74 | CNR2 (0.42) | CNR2HPGDMAPK1HTTADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8945724-B2 | Nitrogen-containing heterocyclic derivative and organic electroluminescent device using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2015-02-03 | — | — | US | disclosed |
| US-8945724-B2 | Nitrogen-containing heterocyclic derivative and organic electroluminescent device using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2015-02-03 | — | — | US | disclosed |
| US-20110012092-A1 | NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2011-01-20 | — | — | US | disclosed |
| US-20110012092-A1 | NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2011-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110012092-A1 | NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | NUDC, TYR, NUDT1 | CNR2 2918/4885MAPT 1953/4885KDM4E 427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.