SCHEMBL12912935

SCHEMBL12912935

c1ccc(-c2c[nH]c(-c3cc(-c4cc(-c5scc(-c6ccccc6)c5-c5ccccc5)cc5ccccc45)c4ccccc4c3)c2-c2ccccc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.35
KMT2A Q03164 4/20 0.35
KDM4E B2RXH2 2/20 0.35
MAPT P10636 2/20 0.35
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
MPI P34949 1/20 0.35
PARP1 P09874 1/20 0.33
IMPDH2 P12268 2/20 0.32
HASPIN Q8TF76 1/20 0.32
CHEK1 O14757 1/20 0.31
EGFR P00533 1/20 0.31
KDR P35968 1/20 0.31
HSD17B1 P14061 1/20 0.31
HSD17B2 P37059 1/20 0.31
HTT P42858 1/20 0.31
MAPK1 P28482 1/20 0.31
HSD17B10 Q99714 1/20 0.31
CDC25B P30305 1/20 0.30
GPR84 Q9NQS5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12912913 0.87 MEN1 (0.44) MEN1KMT2AKDM4EMAPTALDH1A1
SCHEMBL12912882 0.87 KMT2A (0.44) MEN1KMT2AKDM4EMAPTALDH1A1
SCHEMBL12912934 0.81 MAPK8 (0.36) KDM4EMAPTALDH1A1IMPDH2HASPIN
SCHEMBL12912933 0.79 IMPDH2 (0.38) ALDH1A1PARP1IMPDH2CHEK1EGFR
SCHEMBL12912936 0.78 PARP1 (0.38) MEN1KMT2AMAPTALDH1A1PARP1
SCHEMBL12912962 0.74 IMPDH2 (0.31) IMPDH2
SCHEMBL12912963 0.74 CHEK1 (0.36) MEN1KMT2AMAPTIMPDH2CHEK1
SCHEMBL12912938 0.74 CYP2A6 (0.35) MEN1KMT2AKDM4EMAPTPARP1
SCHEMBL12912939 0.72 CHEK1 (0.32) MEN1KMT2AIMPDH2CHEK1EGFR
SCHEMBL24817291 0.72 CYP11B1 (0.41) MEN1KMT2AKDM4EMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7871714-B2 Polymer, electroluminescent device, and light emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-01-18 US disclosed
US-7871714-B2 Polymer, electroluminescent device, and light emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-01-18 US disclosed
US-20090102374-A1 POLYMER, ELECTROLUMINESCENT DEVICE, AND LIGHT EMITTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-04-23 US disclosed
US-20090102374-A1 POLYMER, ELECTROLUMINESCENT DEVICE, AND LIGHT EMITTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-04-23 US disclosed