Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 18/20 | 0.65 |
| ▸ | EGLN2 | Q96KS0 | 12/20 | 0.56 |
| ▸ | EGLN3 | Q9H6Z9 | 12/20 | 0.56 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL962870 | 0.98 | EGLN1 (0.63) | EGLN1EGLN2EGLN3CYSLTR2 | |
| Trifluoroacetic Acid SCHEMBL959313 | 0.88 | EGLN1 (0.52) | EGLN1EGLN2EGLN3CYSLTR2 | |
| SCHEMBL12917928 | 0.87 | EGLN1 (0.52) | EGLN1EGLN2EGLN3CYSLTR2 | |
| SCHEMBL964378 | 0.85 | EGLN1 (0.75) | EGLN1EGLN2EGLN3CYSLTR2 | |
| SCHEMBL14958847 | 0.85 | EGLN1 (0.62) | EGLN1EGLN2EGLN3CYSLTR2 | |
| SCHEMBL962869 | 0.84 | EGLN1 (0.71) | EGLN1EGLN2EGLN3CYSLTR2 | |
| SCHEMBL12917927 | 0.84 | EGLN1 (0.55) | EGLN1EGLN2EGLN3CYSLTR2 | |
| Trifluoroacetic Acid SCHEMBL961435 | 0.83 | EGLN1 (0.55) | EGLN1EGLN2EGLN3CYSLTR2 | |
| SCHEMBL12917939 | 0.83 | EGLN1 (0.56) | EGLN1EGLN2EGLN3CYSLTR2 | |
| Trifluoroacetic Acid SCHEMBL960284 | 0.83 | EGLN1 (0.60) | EGLN1EGLN2EGLN3CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8445680-B2 | Tetrahydrothieno pyridines | MERCK SHARP & DOHME CORP. (US) | 2013-05-21 | — | — | US | disclosed |
| US-20110009425-A1 | TETRAHYDROTHIENO PYRIDINES | MERCK SHARP & DOHME LLC | 2011-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009425-A1 | TETRAHYDROTHIENO PYRIDINES | HIF1AN, HIF1A, EGLN3 | EGLN1 5/4885EGLN2 4/4885EGLN3 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.