Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 20/20 | 0.62 |
| ▸ | EGLN2 | Q96KS0 | 15/20 | 0.61 |
| ▸ | EGLN3 | Q9H6Z9 | 15/20 | 0.61 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL960284 | 0.98 | EGLN1 (0.60) | EGLN1EGLN2EGLN3CYSLTR2 | |
| SCHEMBL12917927 | 0.91 | EGLN1 (0.55) | EGLN1EGLN2EGLN3CYSLTR2 | |
| Trifluoroacetic Acid SCHEMBL961435 | 0.91 | EGLN1 (0.55) | EGLN1EGLN2EGLN3CYSLTR2 | |
| SCHEMBL959312 | 0.90 | EGLN1 (0.76) | EGLN1EGLN2EGLN3CYSLTR2 | |
| SCHEMBL12917937 | 0.89 | EGLN1 (0.53) | EGLN1EGLN2EGLN3CYSLTR2 | |
| SCHEMBL960072 | 0.88 | EGLN1 (0.75) | EGLN1EGLN2EGLN3CYSLTR2 | |
| SCHEMBL12917939 | 0.87 | EGLN1 (0.56) | EGLN1EGLN2EGLN3CYSLTR2 | |
| SCHEMBL12917954 | 0.85 | EGLN1 (0.65) | EGLN1EGLN2EGLN3CYSLTR2 | |
| Trifluoroacetic Acid SCHEMBL959711 | 0.85 | EGLN1 (0.54) | EGLN1EGLN2EGLN3CYSLTR2 | |
| Trifluoroacetic Acid SCHEMBL959313 | 0.84 | EGLN1 (0.52) | EGLN1EGLN2EGLN3CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8445680-B2 | Tetrahydrothieno pyridines | MERCK SHARP & DOHME CORP. (US) | 2013-05-21 | — | — | US | disclosed |