SCHEMBL12919554

SCHEMBL12919554

COc1ccc(-c2ccc(OC(=O)Oc3ccc(C4(c5ccc(OC(C)=O)cc5)CCCCC4)cc3)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.48
MAPT P10636 2/20 0.48
KDM4E B2RXH2 1/20 0.48
CYP2C9 P11712 1/20 0.48
HPGD P15428 1/20 0.48
BACE1 P56817 4/20 0.43
HSD17B10 Q99714 1/20 0.43
ADORA3 P0DMS8 2/20 0.42
POLB P06746 2/20 0.40
MEN1 O00255 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
SLC6A3 Q01959 3/20 0.40
ESR1 P03372 2/20 0.40
SLC6A4 P31645 2/20 0.40
GRIN1 Q05586 1/20 0.40
GRIN2A Q12879 1/20 0.40
GRIN2B Q13224 1/20 0.40
PGR P06401 1/20 0.40
CHRM2 P08172 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12404386 1.00 KMT2A (0.48) KMT2AMAPTKDM4ECYP2C9HPGD
SCHEMBL13144068 0.99 MAPT (0.49) KMT2AMAPTKDM4ECYP2C9HPGD
SCHEMBL19194913 0.96 KMT2A (0.51) KMT2AMAPTKDM4ECYP2C9HPGD
SCHEMBL16488963 0.96 KMT2A (0.51) KMT2AMAPTKDM4ECYP2C9HPGD
SCHEMBL13986180 0.92 KMT2A (0.48) KMT2AMAPTKDM4ECYP2C9HPGD
SCHEMBL12867433 0.92 MAPT (0.45) KMT2AMAPTKDM4ECYP2C9HPGD
SCHEMBL13018397 0.92 MAPT (0.45) KMT2AMAPTKDM4ECYP2C9HPGD
SCHEMBL15417115 0.92 MAPT (0.45) KMT2AMAPTKDM4ECYP2C9HPGD
SCHEMBL14682219 0.92 MAPT (0.45) KMT2AMAPTKDM4ECYP2C9HPGD
SCHEMBL15179068 0.92 MAPT (0.54) KMT2AMAPTKDM4ECYP2C9HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9933712-B2 Multi-layer electrophotographic photosensitive member, process cartridge, and image forming apparatus KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2018-04-03 US disclosed
US-9846378-B2 Electrophotographic photoreceptor, process cartridge, image forming apparatus, and conductive substrate that may be included in electrophotographic photoreceptor FUJI XEROX CO., LTD. (JP) 2017-12-19 US disclosed
US-9829811-B2 Electrophotographic photosensitive member, process cartridge, and image forming apparatus KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2017-11-28 US disclosed
US-20170261874-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, IMAGE FORMING APPARATUS, AND CONDUCTIVE SUBSTRATE THAT MAY BE INCLUDED IN ELECTROPHOTOGRAPHIC PHOTORECEPTOR FUJI XEROX CO., LTD. (JP) 2017-09-14 US disclosed
US-9618881-B2 Biaryl polycarbonate intermediate transfer members XEROX CORPORATION (US) 2017-04-11 US disclosed
US-20170060006-A1 MULTI-LAYER ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2017-03-02 US disclosed
US-20170003608-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2017-01-05 US disclosed
US-9335644-B2 Electron transport material, electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2016-05-10 US disclosed
US-20160085164-A1 ELECTRON TRANSPORT MATERIAL, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJIFILM BUSINESS INNOVATION CORP. (JP) 2016-03-24 US disclosed
US-20150261105-A1 BIPHENYL POLYCARBONATE CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2015-09-17 US disclosed
US-8785090-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2014-07-22 US disclosed
US-20140079446-A1 BIARYL POLYCARBONATE INTERMEDIATE TRANSFER MEMBERS XEROX CORPORATION (US) 2014-03-20 US disclosed
US-20130288169-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2013-10-31 US disclosed
US-20130034733-A1 BIARYL POLYCARBONATE INTERMEDIATE TRANSFER MEMBERS XEROX CORPORATION (US) 2013-02-07 US disclosed
US-20110021739-A1 POLYCARBONATE RESIN MITSUBISHI CHEMICAL CORPORATION (JP) 2011-01-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160085164-A1 ELECTRON TRANSPORT MATERIAL, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS GRK1, NR2E3, ATXN2L KMT2A 4313/4885MAPT 4324/4885KDM4E 4332/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.