SCHEMBL16488963

SCHEMBL16488963

COc1ccc(-c2ccc(C3(c4ccc(-c5ccc(OC(C)=O)cc5)cc4)CCCCC3)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.51
MAPT P10636 2/20 0.51
KDM4E B2RXH2 1/20 0.51
CYP2C9 P11712 1/20 0.51
HPGD P15428 1/20 0.51
BACE1 P56817 4/20 0.47
HSD17B10 Q99714 1/20 0.46
ADORA3 P0DMS8 2/20 0.45
POLB P06746 2/20 0.42
SLC6A3 Q01959 3/20 0.42
ESR1 P03372 2/20 0.42
SLC6A4 P31645 2/20 0.42
GRIN1 Q05586 1/20 0.42
GRIN2A Q12879 1/20 0.42
GRIN2B Q13224 1/20 0.42
PGR P06401 1/20 0.42
CHRM2 P08172 1/20 0.42
AR P10275 1/20 0.42
CHRM1 P11229 1/20 0.42
SLC6A2 P23975 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12919554 0.96 KMT2A (0.48) KMT2AMAPTKDM4ECYP2C9HPGD
SCHEMBL12404386 0.96 KMT2A (0.48) KMT2AMAPTKDM4ECYP2C9HPGD
SCHEMBL26009190 0.96 MAPT (0.54) KMT2AMAPTKDM4ECYP2C9HPGD
SCHEMBL279321 0.96 MAPT (0.54) KMT2AMAPTKDM4ECYP2C9HPGD
SCHEMBL15179068 0.96 MAPT (0.54) KMT2AMAPTKDM4ECYP2C9HPGD
SCHEMBL19268519 0.96 MAPT (0.54) KMT2AMAPTKDM4ECYP2C9HPGD
SCHEMBL13144068 0.94 MAPT (0.49) KMT2AMAPTKDM4ECYP2C9HPGD
SCHEMBL13144066 0.94 MAPT (0.55) KMT2AMAPTKDM4ECYP2C9HPGD
SCHEMBL19194913 0.91 KMT2A (0.51) KMT2AMAPTKDM4ECYP2C9HPGD
SCHEMBL15912532 0.91 MAPT (0.52) KMT2AMAPTKDM4ECYP2C9HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9482969-B2 Imaging members having electrically and mechanically tuned imaging layers XEROX CORPORATION (US) 2016-11-01 US disclosed
US-9091949-B2 Imaging members having electrically and mechanically tuned imaging layers XEROX CORPORATION (US) 2015-07-28 US disclosed
US-9075327-B2 Imaging members and methods for making the same XEROX CORPORATION (US) 2015-07-07 US disclosed
US-20150177629-A1 IMAGING MEMBERS HAVING ELECTRICALLY AND MECHANICALLY TUNED IMAGING LAYERS XEROX CORPORATION 2015-06-25 US disclosed
US-9046798-B2 Imaging members having electrically and mechanically tuned imaging layers XEROX CORPORATION (US) 2015-06-02 US disclosed
US-9017908-B2 Photoelectrical stable imaging members XEROX CORPORATION (US) 2015-04-28 US disclosed
US-20150086914-A1 IMAGING MEMBERS AND METHODS FOR MAKING THE SAME XEROX CORPORATION (US) 2015-03-26 US disclosed
US-20150056546-A1 PHOTOELECTRICAL STABLE IMAGING MEMBERS XEROX CORPORATION (US) 2015-02-26 US disclosed
US-20150050587-A1 IMAGING MEMBERS HAVING ELECTRICALLY AND MECHANICALLY TUNED IMAGING LAYERS XEROX CORPORATION (US) 2015-02-19 US disclosed
US-20150050588-A1 IMAGING MEMBERS HAVING ELECTRICALLY AND MECHANICALLY TUNED IMAGING LAYERS XEROX CORPORATION (US) 2015-02-19 US disclosed