Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 1/20 | 0.68 |
| ▸ | CYP11B1 | P15538 | 7/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CCNC | P24863 | 6/20 | 0.49 |
| ▸ | CDK8 | P49336 | 6/20 | 0.49 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | WNT1 | P04628 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | MYLK | Q15746 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | CILK1 | Q9UPZ9 | 1/20 | 0.44 |
| ▸ | CDK11A | Q9UQ88 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12386960 | 0.81 | PRKCZ (0.69) | PRKCZCYP11B1CYP11B2CYP2D6CYP2C9 | |
| SCHEMBL526801 | 0.81 | PRKCZ (1.00) | PRKCZCYP11B1CYP11B2CYP2D6CYP2C9 | |
| SCHEMBL20095043 | 0.81 | KDR (0.56) | PRKCZCYP2D6CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL12074301 | 0.80 | PRKCZ (0.73) | PRKCZCYP11B1CYP11B2CYP2D6CYP2C9 | |
| SCHEMBL29501875 | 0.80 | PRKCZ (0.72) | PRKCZCYP11B1CYP11B2CYP2D6CYP2C9 | |
| SCHEMBL6243938 | 0.80 | PRKCZ (0.72) | PRKCZCYP11B1CYP11B2CYP2D6CYP2C9 | |
| SCHEMBL23555363 | 0.79 | PRKCZ (0.67) | PRKCZCYP11B1CYP11B2CYP2D6CYP2C9 | |
| SCHEMBL10806364 | 0.78 | PRKCZ (0.69) | PRKCZCYP11B1CYP11B2CYP2D6CYP2C9 | |
| SCHEMBL12074902 | 0.77 | PRKCZ (0.69) | PRKCZCYP11B1CYP11B2CYP2D6CYP2C9 | |
| SCHEMBL38660559 | 0.77 | PRKCZ (0.69) | PRKCZCYP11B1CYP11B2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7871982-B2 | Lincomycin derivatives and antimicrobial agents comprising the same as active ingredient | MEIJI SEIKA KAISHA, LTD. (JP) | 2011-01-18 | — | — | US | disclosed |
| US-7871982-B2 | Lincomycin derivatives and antimicrobial agents comprising the same as active ingredient | MEIJI SEIKA KAISHA, LTD. (JP) | 2011-01-18 | — | — | US | disclosed |
| US-20090156512-A1 | potent activity against resistant pneumococci | MEIJI SEIKA KAISHA, LTD. (JP) | 2009-06-18 | — | — | US | disclosed |
| US-20090156512-A1 | potent activity against resistant pneumococci | MEIJI SEIKA KAISHA, LTD. (JP) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156512-A1 | potent activity against resistant pneumococci | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, NAT1, NPM1 | PRKCZ 4475/4885CYP11B1 886/4885CYP11B2 1407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.