Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP13 | P45452 | 2/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2157135 | 0.91 | USP2 (0.51) | USP2SMN1; SMN2CYP4F2CYP4A11RECQL | |
| SCHEMBL3970403 | 0.85 | PKM (0.49) | USP2SMN1; SMN2CYP4F2CYP4A11RECQL | |
| SCHEMBL28689933 | 0.84 | USP2 (0.45) | USP2SMN1; SMN2CYP4F2CYP4A11TACR1 | |
| SCHEMBL963907 | 0.84 | USP2 (0.47) | USP2SMN1; SMN2CYP4F2CYP4A11RECQL | |
| SCHEMBL28691062 | 0.83 | USP2 (0.44) | USP2SMN1; SMN2CYP4F2CYP4A11TACR1 | |
| SCHEMBL965651 | 0.82 | USP2 (0.51) | USP2SMN1; SMN2CYP4F2CYP4A11TACR1 | |
| SCHEMBL28986539 | 0.82 | USP2 (0.45) | USP2SMN1; SMN2CYP4F2CYP4A11TACR1 | |
| SCHEMBL28797839 | 0.82 | USP2 (0.45) | USP2SMN1; SMN2CYP4F2CYP4A11RECQL | |
| SCHEMBL3160087 | 0.82 | USP2 (0.45) | USP2SMN1; SMN2CYP4F2CYP4A11RECQL | |
| SCHEMBL17830841 | 0.81 | USP2 (0.50) | USP2SMN1; SMN2CYP4F2CYP4A11RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2625178-A1 | BACTERIA TOPOISOMERASE II INHIBITING 2-ETHYLCARBAMOYLAMINO-1, 3-BENZOTHIAZOL-5-YLS | Biota Europe Ltd (GB) | 2013-08-14 | — | — | EP | disclosed |
| WO-2012045124-A1 | BACTERIA TOPOISOMERASE II INHIBITING 2-ETHYLCARBAMOYLAMINO-1, 3-BENZOTHIAZOL-5-YLS | BIOTA EUROPE LTD (GB) | 2012-04-12 | — | — | WO | disclosed |