Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 20/20 | 0.86 |
| ▸ | PDE1A | P54750 | 8/20 | 0.86 |
| ▸ | PDE1B | Q01064 | 8/20 | 0.86 |
| ▸ | PDE1C | Q14123 | 8/20 | 0.86 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.86 |
| ▸ | PDE6A | P16499 | 3/20 | 0.85 |
| ▸ | PDE2A | O00408 | 2/20 | 0.85 |
| ▸ | PDE6D | O43924 | 2/20 | 0.85 |
| ▸ | PDE9A | O76083 | 2/20 | 0.85 |
| ▸ | PDE6G | P18545 | 2/20 | 0.85 |
| ▸ | PDE4A | P27815 | 2/20 | 0.85 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.85 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.85 |
| ▸ | PDE6B | P35913 | 2/20 | 0.85 |
| ▸ | PDE6C | P51160 | 2/20 | 0.85 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.85 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.85 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.85 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.85 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24430082 | 0.97 | PDE5A (0.88) | PDE5APDE1APDE1BPDE1CPDE4B | |
| SCHEMBL12823559 | 0.93 | PDE5A (0.94) | PDE5APDE1APDE1BPDE1CPDE4B | |
| SCHEMBL5537 | 0.93 | PDE5A (1.00) | PDE5APDE1APDE1BPDE1CPDE4B | |
| SCHEMBL30595263 | 0.93 | PDE5A (0.85) | PDE5APDE1APDE1BPDE1CPDE4B | |
| SCHEMBL5931932 | 0.93 | PDE5A (0.85) | PDE5APDE1APDE1BPDE1CPDE4B | |
| SCHEMBL12922534 | 0.93 | PDE5A (0.77) | PDE5APDE1APDE1BPDE1CPDE4B | |
| SCHEMBL14752434 | 0.92 | PDE5A (0.87) | PDE5APDE1APDE1BPDE1CPDE4B | |
| SCHEMBL8259092 | 0.92 | PDE5A (0.84) | PDE5APDE1APDE1BPDE1CPDE4B | |
| SCHEMBL12922557 | 0.92 | PDE5A (0.84) | PDE5APDE1APDE1BPDE1CPDE4B | |
| Vardenafil SCHEMBL29390262 | 0.92 | PDE5A (1.00) | PDE5APDE1APDE1BPDE1CPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117890459-B | Quick screening method for illegally adding chemical drugs into foods based on MSRIT-MS/MS | 南京市食品药品监督检验院 | 2024-10-18 | — | — | CN | claimed |
| CN-117890459-A | Quick screening method for illegally adding chemical drugs into foods based on MSRIT-MS/MS | 南京市食品药品监督检验院 | 2024-04-16 | — | — | CN | claimed |
| CN-117665174-A | Method for detecting PDE5 and SSRI and application thereof | 巴中市产品质量检验检测中心 | 2024-03-08 | — | — | CN | claimed |
| CN-117310032-A | Method for detecting content of illegally added medicines for tonifying kidney and strengthening yang in traditional Chinese medicine | 济宁市食品药品检验检测研究院(济宁市药品不良反应监测中心) | 2023-12-29 | — | — | CN | claimed |
| CN-114878805-B | Preparation method and application of kit for simultaneously detecting multiple nafil substances based on novel multi-quantum dot-protein polymer probe | 华南农业大学 | 2025-04-25 | — | — | CN | disclosed |
| CN-117618527-B | Composition for improving androgen level and male performance, preparation method and application | 山东益衡元健康科技有限公司 | 2024-10-25 | — | — | CN | disclosed |
| CN-117890459-B | Quick screening method for illegally adding chemical drugs into foods based on MSRIT-MS/MS | 南京市食品药品监督检验院 | 2024-10-18 | — | — | CN | disclosed |
| CN-117890459-A | Quick screening method for illegally adding chemical drugs into foods based on MSRIT-MS/MS | 南京市食品药品监督检验院 | 2024-04-16 | — | — | CN | disclosed |
| CN-117665174-A | Method for detecting PDE5 and SSRI and application thereof | 巴中市产品质量检验检测中心 | 2024-03-08 | — | — | CN | disclosed |
| CN-117618527-A | Composition for improving androgen level and male performance, preparation method and application | 山东益衡元健康科技有限公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-117310032-A | Method for detecting content of illegally added medicines for tonifying kidney and strengthening yang in traditional Chinese medicine | 济宁市食品药品检验检测研究院(济宁市药品不良反应监测中心) | 2023-12-29 | — | — | CN | disclosed |
| CN-114308153-B | Solid phase extraction micro-fluidic chip for detecting nafil substances and system for detecting nafil substances | 华南农业大学 | 2023-06-02 | — | — | CN | disclosed |
| US-7704999-B2 | 2-phenyl substituted imidazotriazinones as phosphodiesterase inhibitors | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-04-27 | — | — | US | disclosed |
| US-7704999-B2 | 2-phenyl substituted imidazotriazinones as phosphodiesterase inhibitors | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-04-27 | — | — | US | disclosed |
| US-7696206-B2 | 2-phenyl substituted imidazotriazinones as phosphodiesterase inhibitors | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-04-13 | — | — | US | disclosed |
| US-20100016323-A1 | 2-PHENYL SUBSTITUTED IMIDAZOTRIAZINONES AS PHOSPHODIESTERASE INHIBITORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-01-21 | — | — | US | disclosed |
| US-20080113972-A1 | 2-Phenyl substituted imidazotriazinones as phosphodiesterase inhibitors | BAYER AKTIENGESELLSCHAFT (DE) | 2008-05-15 | — | — | US | disclosed |
| US-20080113972-A1 | 2-Phenyl substituted imidazotriazinones as phosphodiesterase inhibitors | BAYER AKTIENGESELLSCHAFT (DE) | 2008-05-15 | — | — | US | disclosed |
| US-7314871-B2 | 2-phenyl substituted imidazotriazinones as phosphodiesterase inhibitors, for treatment of hypertension | BAYER AKTIENGESELLSCHAFT (DE) | 2008-01-01 | — | — | US | disclosed |
| US-7314871-B2 | 2-phenyl substituted imidazotriazinones as phosphodiesterase inhibitors, for treatment of hypertension | BAYER AKTIENGESELLSCHAFT (DE) | 2008-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016323-A1 | 2-PHENYL SUBSTITUTED IMIDAZOTRIAZINONES AS PHOSPHODIESTERASE INHIBITORS | PDE3A, PDE2A, PDE3B | PDE5A 4/4885PDE1A 18/4885PDE1B 21/4885 |
| US-20080113972-A1 | 2-Phenyl substituted imidazotriazinones as phosphodiesterase inhibitors | PDE3B, PDE3A, PDE2A | PDE5A 4/4885PDE1A 25/4885PDE1B 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.