⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1240634 | 0.97 | SHBG (0.43) | — | |
| SCHEMBL20594181 | 0.97 | SHBG (0.43) | — | |
| SCHEMBL20594356 | 0.97 | SHBG (0.43) | — | |
| SCHEMBL21469 | 0.97 | — | — | |
| SCHEMBL6673265 | 0.97 | SHBG (0.43) | — | |
| SCHEMBL126871 | 0.93 | — | — | |
| SCHEMBL28332 | 0.86 | — | — | |
| SCHEMBL8010131 | 0.78 | SHBG (0.38) | — | |
| SCHEMBL7840128 | 0.75 | CPN1 (0.41) | — | |
| SCHEMBL8009630 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 873 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112898286-A | Benzothiophene compound or pharmaceutically acceptable salt and isomer thereof, and preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2021-06-04 | — | — | CN | claimed |
| CN-105085429-B | Aromatic heterocyclic derivative and application thereof in medicines | 广东东阳光药业有限公司 | 2019-12-10 | — | — | CN | claimed |
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | claimed |
| WO-2015161830-A1 | HETEROAROMATIC DERIVATIVES AND PHARMACEUTICAL APPLICATIONS THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-10-29 | — | — | WO | claimed |
| EP-1852420-B1 | Indole compounds for treating respiratory disorders | ONO PHARMACEUTICAL CO (JP) | 2012-10-17 | — | — | EP | claimed |
| US-20110077234-A1 | Urea Glucokinase Activators | NOVO NORDISK A/S (DK) | 2011-03-31 | — | — | US | claimed |
| US-7884210-B2 | {2-[3-(2-Cyclohex-1-enyl-ethyl)-3-(trans-4-methyl-cyclohexyl)-ureido]-thiazol-5-ylsulfanyl}-acetic acid; for treatment of type 2 diabetes | NOVO NORDISK A/S (DK) | 2011-02-08 | — | — | US | claimed |
| US-20090105482-A1 | Urea Glucokinase Activators | NOVO NORDISK A/S (DK) | 2009-04-23 | — | — | US | claimed |
| JP-2009501198-A | — | — | 2009-01-15 | — | — | JP | claimed |
| EP-1904467-A1 | UREA GLUCOKINASE ACTIVATORS | Novo Nordisk A/S (DK) | 2008-04-02 | — | — | EP | claimed |
| WO-2007006814-A1 | UREA GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2007-01-18 | — | — | WO | claimed |
| US-4348393-A | ANTIDEPRESSANTS | DELALANDE S.A. (FR) | 1982-09-07 | — | — | US | claimed |
| CN-112279864-B | Difunctional coumarin oxime ester compound and preparation and application thereof | 湖北固润科技股份有限公司 | 2024-07-16 | — | — | CN | disclosed |
| EP-4396173-A1 | HERBICIDAL MALONAMIDES CONTAINING A CONDENSED RING SYSTEM | BASF SE (DE) | 2024-07-10 | — | — | EP | disclosed |
| EP-4396163-A1 | HERBICIDAL MALONAMIDES CONTAINING MONOCYCLIC HETEROAROMATIC RINGS | BASF SE (DE) | 2024-07-10 | — | — | EP | disclosed |
| WO-2024137629-A1 | AZOLE COMPOUNDS FOR CONTROLLING AND COMBATING INVERTEBRATE PESTS | FMC CORPORATION (US) | 2024-06-27 | — | — | WO | disclosed |
| US-4526786-A | N-Substituted phenyl-5-aminomethyl oxazolidinones and their method of use | DELALANDE S.A. (FR) | 1985-07-02 | — | — | US | disclosed |
| US-4435415-A | ANTIDEPRESSANTS | DELALANDE S.A. (FR) | 1984-03-06 | — | — | US | disclosed |
| US-4348393-A | ANTIDEPRESSANTS | DELALANDE S.A. (FR) | 1982-09-07 | — | — | US | disclosed |
| US-4287351-A | USEFUL AS ANTIDEPRESSANTS | DELALANDE S.A. (FR) | 1981-09-01 | — | — | US | disclosed |