Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | NPC1 | O15118 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | SCP2 | P22307 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 10/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12925194 | 0.93 | MEN1 (0.64) | RAB9AMEN1NPC1KMT2APOLB | |
| SCHEMBL12925166 | 0.93 | MEN1 (0.64) | RAB9AMEN1NPC1KMT2APOLB | |
| SCHEMBL31235518 | 0.93 | MEN1 (0.64) | RAB9AMEN1NPC1KMT2APOLB | |
| SCHEMBL995698 | 0.93 | MEN1 (0.64) | RAB9AMEN1NPC1KMT2APOLB | |
| SCHEMBL995700 | 0.93 | MEN1 (0.64) | RAB9AMEN1NPC1KMT2APOLB | |
| SCHEMBL997675 | 0.90 | MEN1 (0.61) | RAB9AMEN1NPC1KMT2APOLB | |
| SCHEMBL997673 | 0.90 | MEN1 (0.61) | RAB9AMEN1NPC1KMT2APOLB | |
| SCHEMBL12925202 | 0.90 | MEN1 (0.61) | RAB9AMEN1NPC1KMT2APOLB | |
| SCHEMBL5858873 | 0.90 | RAB9A (0.63) | RAB9AMEN1NPC1KMT2APOLB | |
| SCHEMBL5858870 | 0.90 | RAB9A (0.63) | RAB9AMEN1NPC1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2269996-B1 | MEDICINAL COMPOSITION CONTAINING BENZO[A]PHENOXANTHIN COMPOUND AS THE ACTIVE INGREDIENT FOR PREVENTING OR TREATING PROTOZOAL DISEASE | HOSHI UNIVERSITY (JP) | 2012-10-17 | — | — | EP | disclosed |
| US-8288374-B2 | Medicinal composition containing benzo[a]phenoxazine compound as the active ingredient for prevention or treatment of protozoal disease | HOSHI UNIVERSITY (JP) | 2012-10-16 | — | — | US | disclosed |
| US-8288374-B2 | Medicinal composition containing benzo[a]phenoxazine compound as the active ingredient for prevention or treatment of protozoal disease | HOSHI UNIVERSITY (JP) | 2012-10-16 | — | — | US | disclosed |
| US-20110021450-A1 | MEDICINAL COMPOSITION CONTAINING BENZO[A]PHENOXAZINE COMPOUND AS THE ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF PROTOZOAL DISEASE | HOSHI UNIVERSITY (JP) | 2011-01-27 | — | — | US | disclosed |
| US-20110021450-A1 | MEDICINAL COMPOSITION CONTAINING BENZO[A]PHENOXAZINE COMPOUND AS THE ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF PROTOZOAL DISEASE | HOSHI UNIVERSITY (JP) | 2011-01-27 | — | — | US | disclosed |
| EP-2269996-A1 | MEDICINAL COMPOSITION CONTAINING BENZO[A]PHENOXANTHIN COMPOUND AS THE ACTIVE INGREDIENT FOR PREVENTING OR TREATING PROTOZOAL DISEASE | Hoshi University (JP) | 2011-01-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021450-A1 | MEDICINAL COMPOSITION CONTAINING BENZO[A]PHENOXAZINE COMPOUND AS THE ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF PROTOZOAL DISEASE | TBCA, THPO, PAOX | RAB9A 3315/4885MEN1 3404/4885NPC1 2025/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.