Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 8/20 | 0.66 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.66 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | HRH1 | P35367 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2074712 | 0.86 | SLC6A4 (0.67) | SLC6A4SLC6A2CYP2D6KCNH2HTR2A | |
| SCHEMBL2075044 | 0.86 | SLC6A4 (0.67) | SLC6A4SLC6A2CYP2D6KCNH2HTR2A | |
| SCHEMBL2074877 | 0.85 | SLC6A4 (0.66) | SLC6A4SLC6A2CYP2D6KCNH2HTR2A | |
| SCHEMBL2071176 | 0.84 | SLC6A4 (0.64) | SLC6A4SLC6A2CYP2D6KCNH2HTR2A | |
| SCHEMBL2071079 | 0.82 | SLC6A4 (0.63) | SLC6A4SLC6A2CYP2D6KCNH2HTR2A | |
| SCHEMBL2073574 | 0.81 | SLC6A4 (0.62) | SLC6A4SLC6A2CYP2D6KCNH2HTR2A | |
| SCHEMBL2073872 | 0.81 | SLC6A4 (0.67) | SLC6A4SLC6A2CYP2D6KCNH2HTR2A | |
| SCHEMBL2074259 | 0.80 | SLC6A4 (0.59) | SLC6A4SLC6A2CYP2D6KCNH2HTR2A | |
| SCHEMBL2074218 | 0.80 | SLC6A4 (1.00) | SLC6A4SLC6A2CYP2D6KCNH2HTR2A | |
| SCHEMBL2073941 | 0.77 | SLC6A4 (0.50) | SLC6A4SLC6A2CYP2D6KCNH2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7863305-B2 | 3-amino-1-arylpropyl indoles as monoamine reuptake inhibitors | ROCHE PALO ALTO LLC (US) | 2011-01-04 | — | — | US | disclosed |
| US-7863305-B2 | 3-amino-1-arylpropyl indoles as monoamine reuptake inhibitors | ROCHE PALO ALTO LLC (US) | 2011-01-04 | — | — | US | disclosed |