⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formaldehyde SCHEMBL28299249 | 0.69 | — | — | |
| SCHEMBL2842864 | 0.63 | — | — | |
| Thiazole-5-Carbaldehyde SCHEMBL1316528 | 0.63 | PIM1 (0.42) | — | |
| Thiazole-5-Carbaldehyde SCHEMBL194323 | 0.63 | — | — | |
| SCHEMBL544073 | 0.63 | — | — | |
| SCHEMBL5752803 | 0.63 | KMT2A (0.47) | — | |
| SCHEMBL2840541 | 0.63 | — | — | |
| SCHEMBL290048 | 0.62 | — | — | |
| SCHEMBL1162452 | 0.62 | — | — | |
| SCHEMBL276437 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 924 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230364115-A1 | NOVEL PSYCHEDELIC COMPOSITIONS, DELIVERY SYSTEMS AND THERAPEUTIC USES THEREOF | MYDECINE INNOVATIONS GROUP INC (US) | 2023-11-16 | — | — | US | claimed |
| EP-4273147-A1 | SUBSTITUTED SPIROLACTAMS, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | Bayer Aktiengesellschaft (DE) | 2023-11-08 | — | — | EP | claimed |
| CN-116234546-A | GPX4 inhibitors, pharmaceutical compositions thereof and their use in the treatment of GPX4 mediated diseases | 嘉兴优博生物技术有限公司 | 2023-06-06 | — | — | CN | claimed |
| US-20230132298-A1 | OXABOROLE ESTERS AND USES THEREOF | ANACOR PHARMACEUTICALS, LLC | 2023-04-27 | — | — | US | claimed |
| US-11578087-B2 | Oxaborole esters and uses thereof | ANACOR PHARMACEUTICALS, INC. (US) | 2023-02-14 | — | — | US | claimed |
| CN-115417829-A | Preparation method of ritonavir enantiomer | 武汉海特生物创新医药研究有限公司 | 2022-12-02 | — | — | CN | claimed |
| US-11186596-B2 | Anticancer indenes, indanes, azaindenes, azaindanes, pharmaceutical compositions and uses | ADT PHARMACEUTICALS, LLC (US) | 2021-11-30 | — | — | US | claimed |
| WO-2021183702-A1 | GPX4 INHIBITORS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR USE FOR TREATING GPX4-MEDIATED DISEASES | EUBULUS BIOTHERAPEUTICS INC. (CN) | 2021-09-16 | — | — | WO | claimed |
| US-20210220333-A1 | COMPOSITIONS AND METHODS FOR PREVENTING AND/OR TREATING FILARIAL DISEASE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2021-07-22 | — | — | US | claimed |
| EP-3846817-A1 | COMPOSITIONS AND METHODS FOR PREVENTING AND/OR TREATING FILARIAL DISEASE | The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (US) | 2021-07-14 | — | — | EP | claimed |
| US-5683999-A | Cyclic urea HIV protease inhibitors | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-11-04 | — | — | US | claimed |
| WO-1996029329-A1 | CYCLIC UREA HIV PROTEASE INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-09-26 | — | — | WO | claimed |
| US-5395838-A | Aromatic aminomethyl substitutes compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1995-03-07 | — | — | US | claimed |
| US-5393875-A | Hypotensive, cardiotonic and antiischemic agents | HOFFMANN-LA ROCHE INC. (US) | 1995-02-28 | — | — | US | claimed |
| EP-0373891-B1 | Anti-tumour agents | ICI PLC (GB) | 1994-11-02 | — | — | EP | claimed |
| US-5189165-A | PROCESS FOR THE PREPARATION OF 1,1-DISUBSTITUTED CYCLOPROPANE DERIVATIVES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-02-23 | — | — | US | claimed |
| EP-0509354-A2 | Amino acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1992-10-21 | — | — | EP | claimed |
| EP-0435151-A2 | Process for the preparation of 1,1-disubstituted cyclopropane derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-07-03 | — | — | EP | claimed |
| EP-0373891-A2 | Anti-tumour agents | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-06-20 | — | — | EP | claimed |
| EP-0237917-A2 | 1,1-Disubstituted cyclopropane derivatives, processes for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-09-23 | — | — | EP | claimed |