SCHEMBL12938503

SCHEMBL12938503

Fc1ccc(-c2nc3ccccc3nc2-c2ccc(C(F)(F)F)cc2)cc1

nearest known ligand 0.69

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 7/20 0.69
MAPK10 P53779 2/20 0.69
AKT1 P31749 1/20 0.56
AKT2 P31751 1/20 0.56
KDM4E B2RXH2 2/20 0.49
NPSR1 Q6W5P4 1/20 0.49
KIF11 P52732 1/20 0.48
DHFR P00374 2/20 0.48
TOP1 P11387 1/20 0.48
CFTR P13569 1/20 0.47
ADORA2A P29274 1/20 0.46
LMNA P02545 1/20 0.46
GAA P10253 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
ABCG2 Q9UNQ0 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2961284 0.93 AKT1 (0.62) MAPK14MAPK10AKT1AKT2KDM4E
SCHEMBL71619 0.87 MAPK14 (0.81) MAPK14MAPK10AKT1AKT2KDM4E
SCHEMBL29405271 0.87 MAPK14 (0.81) MAPK14MAPK10AKT1AKT2KDM4E
SCHEMBL19470951 0.86 AKT1 (0.56) MAPK14MAPK10AKT1AKT2KDM4E
SCHEMBL27962380 0.85 MAPK14 (0.78) MAPK14MAPK10AKT1AKT2KDM4E
SCHEMBL29767839 0.85 MAPK14 (0.78) MAPK14MAPK10AKT1AKT2KDM4E
SCHEMBL28252524 0.85 MAPK14 (0.78) MAPK14MAPK10AKT1AKT2KDM4E
SCHEMBL29596631 0.85 MAPK14 (0.78) MAPK14MAPK10AKT1AKT2KDM4E
SCHEMBL28215884 0.83 MAPK14 (0.75) MAPK14MAPK10AKT1AKT2KDM4E
SCHEMBL23628257 0.81 KDM4E (0.65) MAPK14MAPK10AKT1AKT2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9296848-B2 Polymer material, solar cell using the same, and solar photovoltaic generation system KABUSHIKI KAISHA TOSHIBA (JP) 2016-03-29 US disclosed
US-20120248878-A1 POLYMER MATERIAL, SOLAR CELL USING THE SAME, AND SOLAR PHOTOVOLTAIC GENERATION SYSTEM KABUSHIKI KAISHA TOSHIBA (JP) 2012-10-04 US disclosed