SCHEMBL28252524

SCHEMBL28252524

Fc1ccc(-c2nc3ccccc3nc2-c2ccc(F)cc2)cc1.Fc1ccc(-c2nc3ccccc3nc2-c2ccc(F)cc2)cc1.[Ir]

nearest known ligand 0.78

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 12/20 0.78
MAPK10 P53779 2/20 0.78
KDM4E B2RXH2 3/20 0.55
LMNA P02545 2/20 0.55
L3MBTL1 Q9Y468 2/20 0.55
TDP1 Q9NUW8 2/20 0.55
GAA P10253 1/20 0.55
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
ADORA2A P29274 1/20 0.55
ALDH1A1 P00352 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
AKT1 P31749 1/20 0.47
AKT2 P31751 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27962380 1.00 MAPK14 (0.78) MAPK14MAPK10KDM4ELMNAL3MBTL1
SCHEMBL29405271 0.98 MAPK14 (0.81) MAPK14MAPK10KDM4ELMNAL3MBTL1
SCHEMBL71619 0.98 MAPK14 (0.81) MAPK14MAPK10KDM4ELMNAL3MBTL1
SCHEMBL29596631 0.95 MAPK14 (0.78) MAPK14MAPK10KDM4ELMNAL3MBTL1
SCHEMBL29767839 0.95 MAPK14 (0.78) MAPK14MAPK10KDM4ELMNAL3MBTL1
SCHEMBL28215884 0.93 MAPK14 (0.75) MAPK14MAPK10KDM4ELMNAL3MBTL1
SCHEMBL17656946 0.90 MAPK14 (0.70) MAPK14MAPK10KDM4ELMNAL3MBTL1
SCHEMBL14819322 0.88 TDP1 (0.75) MAPK14MAPK10KDM4ELMNAL3MBTL1
Quinoxaline SCHEMBL6431397 0.88 MAPK14 (0.73) MAPK14MAPK10KDM4ELMNAL3MBTL1
SCHEMBL12938503 0.85 MAPK14 (0.69) MAPK14MAPK10KDM4ELMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118388374-A Organometallic complexes 株式会社半导体能源研究所 2024-07-26 CN disclosed
CN-110383522-A Light-emitting element material, light-emitting component, light emitting device, electronic equipment, lighting device and organometallic complex 株式会社半导体能源研究所 2019-10-25 CN disclosed
CN-107230744-B Light-emitting component, light emitting device, electronic equipment and lighting device 株式会社半导体能源研究所 2019-03-08 CN disclosed
CN-105037339-B Heterocyclic compound 株式会社半导体能源研究所 2018-11-20 CN disclosed
CN-106711344-B Light-emitting component, light-emitting device, electronic equipment and lighting device 株式会社半导体能源研究所 2018-11-09 CN disclosed