Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | GFER | P55789 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12944473 | 0.85 | GRIN1 (0.51) | KMT2AGFERALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL12944502 | 0.81 | HRH3 (0.50) | KMT2AGFERMAPTSMN1; SMN2HTT | |
| SCHEMBL12944504 | 0.80 | MAPT (0.44) | KMT2AGFERHSD17B10ALDH1A1KDM4E | |
| SCHEMBL4375437 | 0.79 | KMT2A (0.72) | KMT2AGFERHSD17B10ALDH1A1KDM4E | |
| SCHEMBL12944394 | 0.78 | CCR1 (0.46) | KMT2ARAB9AMEN1 | |
| SCHEMBL12944501 | 0.75 | SMN1; SMN2 (0.45) | KMT2AALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL3007671 | 0.75 | KMT2A (0.55) | KMT2AGFERALDH1A1KDM4EHPGD | |
| SCHEMBL12944648 | 0.74 | MEN1 (0.51) | KMT2AALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL12944653 | 0.74 | MAPK1 (0.62) | KMT2AALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL12943988 | 0.74 | ENPP2 (0.52) | KMT2AALDH1A1KDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011002067-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF | 武田薬品工業株式会社 (JP) | 2011-01-06 | — | — | WO | disclosed |