Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 11/20 | 0.69 |
| ▸ | KIF11 | P52732 | 6/20 | 0.43 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL937831 | 0.87 | SCN5A (0.69) | SCN5AKIF11SCN1ASCN2AKDM4E | |
| SCHEMBL12909209 | 0.86 | SCN5A (0.68) | SCN5ASSTR4SCN1ASCN2AKDM4E | |
| SCHEMBL20209249 | 0.84 | SCN5A (0.62) | SCN5ASSTR4SCN1ASCN2ACYP1A2 | |
| SCHEMBL20209632 | 0.83 | SCN5A (0.49) | SCN5AKIF11SSTR4KDM4EALDH1A1 | |
| SCHEMBL935897 | 0.82 | SCN5A (1.00) | SCN5ASCN1ASCN2ACYP1A2 | |
| SCHEMBL932813 | 0.82 | SCN5A (0.75) | SCN5ASCN1ASCN2AKDM4EALDH1A1 | |
| SCHEMBL26461783 | 0.82 | SCN5A (0.63) | SCN5AKIF11SSTR4SCN1ASCN2A | |
| SCHEMBL936582 | 0.81 | SCN5A (0.73) | SCN5ASCN1ASCN2ACYP1A2 | |
| SCHEMBL1160465 | 0.80 | SCN5A (0.60) | SCN5AKIF11SSTR4HPGD | |
| SCHEMBL936772 | 0.80 | SCN5A (0.71) | SCN5ASCN1ASCN2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110021521-A1 | FUSED HETEROCYCLIC COMPOUNDS AS ION CHANNEL MODULATORS | GILEAD PALO ALTO, INC. (US) | 2011-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021521-A1 | FUSED HETEROCYCLIC COMPOUNDS AS ION CHANNEL MODULATORS | KCNJ2, KCNH2, KCNA3 | SCN5A 52/4885KIF11 4034/4885SSTR4 1483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.