Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 8/20 | 0.60 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12909209 | 0.81 | SCN5A (0.68) | SCN5AMAPTSMN1; SMN2SSTR4 | |
| SCHEMBL937831 | 0.80 | SCN5A (0.69) | SCN5AKIF11MAPT | |
| SCHEMBL12945003 | 0.80 | SCN5A (0.69) | SCN5AKIF11SSTR4HPGD | |
| SCHEMBL932813 | 0.78 | SCN5A (0.75) | SCN5ASMN1; SMN2HPGD | |
| SCHEMBL20209249 | 0.77 | SCN5A (0.62) | SCN5ASSTR4 | |
| SCHEMBL936530 | 0.77 | SCN5A (0.66) | SCN5AKIF11MAPTSMN1; SMN2HSD17B1 | |
| SCHEMBL937557 | 0.69 | SCN5A (0.59) | SCN5AMAPTSYK | |
| SCHEMBL23499863 | 0.69 | KIF11 (0.50) | KIF11MAPTSMN1; SMN2HSD17B1SYK | |
| SCHEMBL936494 | 0.69 | SCN5A (0.54) | SCN5ASSTR4 | |
| SCHEMBL938447 | 0.68 | SCN5A (0.54) | SCN5ASSTR4MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2464645-A1 | FUSED HETEROCYCLIC COMPOUNDS AS ION CHANNEL MODULATORS | Gilead Palo Alto, Inc. (US) | 2012-06-20 | — | — | EP | claimed |
| WO-2011014462-A1 | FUSED HETEROCYCLIC COMPOUNDS AS ION CHANNEL MODULATORS | GILEAD PALO ALTO, INC. (US) | 2011-02-03 | — | — | WO | claimed |