Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10389540 | 1.00 | CHRM2 (0.43) | CHRM2CHRM4CHRM3SLC6A2SLC6A4 | |
| SCHEMBL10389542 | 1.00 | CHRM2 (0.43) | CHRM2CHRM4CHRM3SLC6A2SLC6A4 | |
| SCHEMBL262052 | 1.00 | CHRM2 (0.43) | CHRM2CHRM4CHRM3SLC6A2SLC6A4 | |
| SCHEMBL27265137 | 1.00 | CHRM2 (0.43) | CHRM2CHRM4CHRM3SLC6A2SLC6A4 | |
| SCHEMBL7076034 | 0.98 | SLC6A2 (0.45) | CHRM2CHRM4CHRM3SLC6A2SLC6A4 | |
| SCHEMBL23921599 | 0.95 | CHRM2 (0.47) | CHRM2CHRM4CHRM3SLC6A2SLC6A4 | |
| SCHEMBL8384596 | 0.95 | CHRM2 (0.47) | CHRM2CHRM4CHRM3SLC6A2SLC6A4 | |
| SCHEMBL2693326 | 0.95 | CHRM2 (0.47) | CHRM2CHRM4CHRM3SLC6A2SLC6A4 | |
| SCHEMBL7079357 | 0.95 | CHRM2 (0.47) | CHRM2CHRM4CHRM3SLC6A2SLC6A4 | |
| SCHEMBL7191976 | 0.95 | CHRM2 (0.47) | CHRM2CHRM4CHRM3SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7875707-B2 | combinatorial libraries; lipid solubility; solid phase synthesis | ALCHEMIA LIMITED (AU) | 2011-01-25 | — | — | US | disclosed |