Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17975257 | 1.00 | CYP1A2 (0.34) | CYP1A2CYP2C9 | |
| SCHEMBL17975265 | 1.00 | CYP1A2 (0.34) | CYP1A2CYP2C9 | |
| SCHEMBL17975258 | 0.91 | CYP1A2 (0.36) | CYP1A2CYP2C9 | |
| SCHEMBL17975259 | 0.91 | CYP1A2 (0.36) | CYP1A2CYP2C9 | |
| SCHEMBL17975264 | 0.91 | CYP1A2 (0.36) | CYP1A2CYP2C9 | |
| SCHEMBL17975263 | 0.91 | CYP1A2 (0.36) | CYP1A2CYP2C9 | |
| SCHEMBL17975255 | 0.91 | CYP1A2 (0.38) | CYP1A2CYP2C9 | |
| SCHEMBL13942779 | 0.91 | CYP1A2 (0.38) | CYP1A2CYP2C9 | |
| SCHEMBL17975256 | 0.91 | CYP1A2 (0.38) | CYP1A2CYP2C9 | |
| SCHEMBL13686075 | 0.83 | CYP1A2 (0.39) | CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7872029-B2 | Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states | BOWEN J PHILLIP | 2011-01-18 | — | — | US | disclosed |
| US-20090018167-A1 | Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states | Robinson, Thomas Philip (US) | 2009-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018167-A1 | Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states | FLT1, FLT4, VEGFA | CYP1A2 792/4885CYP2C9 1737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.