Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.36 |
| ▸ | F3 | P13726 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17975258 | 1.00 | CYP1A2 (0.36) | CYP1A2F3EGFRNFE2L2MAPT | |
| SCHEMBL17975259 | 1.00 | CYP1A2 (0.36) | CYP1A2F3EGFRNFE2L2MAPT | |
| SCHEMBL17975264 | 1.00 | CYP1A2 (0.36) | CYP1A2F3EGFRNFE2L2MAPT | |
| SCHEMBL12948751 | 0.91 | CYP1A2 (0.34) | CYP1A2CYP2C9 | |
| SCHEMBL17975265 | 0.91 | CYP1A2 (0.34) | CYP1A2CYP2C9 | |
| SCHEMBL17975257 | 0.91 | CYP1A2 (0.34) | CYP1A2CYP2C9 | |
| SCHEMBL17975284 | 0.91 | CYP1A2 (0.34) | CYP1A2CYP2C9 | |
| SCHEMBL17975266 | 0.91 | CYP1A2 (0.34) | CYP1A2CYP2C9 | |
| SCHEMBL17975262 | 0.91 | CYP1A2 (0.41) | CYP1A2F3EGFRNFE2L2MAPT | |
| SCHEMBL17975261 | 0.91 | CYP1A2 (0.41) | CYP1A2F3EGFRNFE2L2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160374997-A1 | ANTIBIOTIC COMPOUNDS THAT INHIBIT BACTERIAL PROTEIN SYNTHESIS | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2016-12-29 | — | — | US | disclosed |
| US-20160220510-A1 | ANTIBIOTIC COMPOUNDS THAT INHIBIT BACTERIAL PROTEIN SYNTHESIS | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2016-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160374997-A1 | ANTIBIOTIC COMPOUNDS THAT INHIBIT BACTERIAL PROTEIN SYNTHESIS | AARS1, EPRS1, EEF1G | CYP1A2 3382/4885F3 780/4885EGFR 373/4885 |
| US-20160220510-A1 | ANTIBIOTIC COMPOUNDS THAT INHIBIT BACTERIAL PROTEIN SYNTHESIS | AARS1, EPRS1, EEF1G | CYP1A2 3382/4885F3 780/4885EGFR 373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.