Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11999764 | 0.89 | CYP1A2 (0.34) | CYP1A2 | |
| SCHEMBL6446752 | 0.89 | CYP1A2 (0.34) | CYP1A2 | |
| SCHEMBL12922698 | 0.89 | CYP1A2 (0.34) | CYP1A2 | |
| SCHEMBL182830 | 0.80 | — | — | |
| SCHEMBL14599339 | 0.80 | — | — | |
| SCHEMBL2589699 | 0.80 | — | — | |
| SCHEMBL28588977 | 0.76 | KEAP1 (0.30) | — | |
| SCHEMBL17633955 | 0.73 | CNR1 (0.33) | — | |
| SCHEMBL12002047 | 0.73 | CNR1 (0.33) | — | |
| SCHEMBL7898886 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7872029-B2 | Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states | BOWEN J PHILLIP | 2011-01-18 | — | — | US | disclosed |