Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 2/20 | 0.39 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL939460 | 1.00 | NR1I2 (0.39) | NR1I2CYP2E1 | |
| SCHEMBL939459 | 1.00 | NR1I2 (0.39) | NR1I2CYP2E1 | |
| SCHEMBL939434 | 0.97 | NR1I2 (0.40) | NR1I2CYP2E1 | |
| SCHEMBL939433 | 0.97 | NR1I2 (0.40) | NR1I2CYP2E1 | |
| SCHEMBL12949359 | 0.94 | NR1I2 (0.33) | NR1I2 | |
| SCHEMBL12949479 | 0.94 | NR1I2 (0.34) | NR1I2 | |
| SCHEMBL938033 | 0.88 | NR1I2 (0.45) | NR1I2CYP2E1 | |
| SCHEMBL938035 | 0.88 | NR1I2 (0.45) | NR1I2CYP2E1 | |
| SCHEMBL12909605 | 0.88 | NR1I2 (0.52) | NR1I2CYP2E1 | |
| SCHEMBL12909879 | 0.88 | NR1I2 (0.52) | NR1I2CYP2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011011303-A1 | INHIBITORS OF FLAVIVIRIDAE VIRUSES | GILEAD SCIENCES, INC. (US) | 2011-01-27 | — | — | WO | disclosed |