Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL939460 | 0.94 | NR1I2 (0.39) | NR1I2 | |
| SCHEMBL12949309 | 0.94 | NR1I2 (0.39) | NR1I2 | |
| SCHEMBL939459 | 0.94 | NR1I2 (0.39) | NR1I2 | |
| SCHEMBL12949479 | 0.94 | NR1I2 (0.34) | NR1I2 | |
| SCHEMBL939434 | 0.92 | NR1I2 (0.40) | NR1I2 | |
| SCHEMBL939433 | 0.92 | NR1I2 (0.40) | NR1I2 | |
| SCHEMBL15015416 | 0.83 | NR1I2 (0.33) | NR1I2 | |
| SCHEMBL938033 | 0.82 | NR1I2 (0.45) | NR1I2 | |
| SCHEMBL938035 | 0.82 | NR1I2 (0.45) | NR1I2 | |
| SCHEMBL12909605 | 0.82 | NR1I2 (0.52) | NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2475657-B1 | 5-ALKINYLTHIEN-2-YLCARBOXYLIC ACIDS AS INHIBITORS OF FLAVIVIRIDAE VIRUSES | GILEAD SCIENCES INC (US) | 2013-06-12 | — | — | EP | disclosed |
| WO-2011011303-A1 | INHIBITORS OF FLAVIVIRIDAE VIRUSES | GILEAD SCIENCES, INC. (US) | 2011-01-27 | — | — | WO | disclosed |