Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | IKBKB | O14920 | 1/20 | 0.48 |
| ▸ | RAF1 | P04049 | 10/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL173108 | 0.87 | RAF1 (0.56) | KDM4EMAPTNPC1CASP3RAB9A | |
| Hydrochloric Acid SCHEMBL11007849 | 0.81 | IKBKB (0.51) | KDM4EMAPTNPC1CASP3RAB9A | |
| SCHEMBL3239031 | 0.78 | KDM4E (0.54) | KDM4EMAPTNPC1CASP3RAB9A | |
| SCHEMBL166726 | 0.74 | MAPT (0.54) | KDM4EMAPTNPC1CASP3RAB9A | |
| SCHEMBL24523710 | 0.73 | KDM4E (0.53) | KDM4EMAPTNPC1CASP3RAB9A | |
| SCHEMBL12523092 | 0.73 | KDM4E (0.53) | KDM4EMAPTNPC1CASP3RAB9A | |
| SCHEMBL10566679 | 0.73 | KDM4E (0.60) | KDM4EMAPTNPC1CASP3RAB9A | |
| Hydrochloric Acid SCHEMBL10735502 | 0.73 | MAPT (0.53) | KDM4EMAPTNPC1CASP3RAB9A | |
| SCHEMBL318526 | 0.73 | KDM4E (0.53) | KDM4EMAPTNPC1CASP3RAB9A | |
| SCHEMBL102283 | 0.73 | KDM4E (0.53) | KDM4EMAPTNPC1CASP3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011011303-A1 | INHIBITORS OF FLAVIVIRIDAE VIRUSES | GILEAD SCIENCES, INC. (US) | 2011-01-27 | — | — | WO | disclosed |