Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 13/20 | 0.69 |
| ▸ | CDK2 | P24941 | 8/20 | 0.54 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13118885 | 0.91 | GSK3B (0.69) | GSK3BCDK2CCNE1 | |
| SCHEMBL14545239 | 0.91 | GSK3B (0.55) | GSK3BCDK2CCNE1 | |
| SCHEMBL13118987 | 0.90 | GSK3B (0.69) | GSK3BCDK2CCNE1 | |
| SCHEMBL13121515 | 0.88 | GSK3B (0.69) | GSK3BCDK2CCNE1 | |
| SCHEMBL13121487 | 0.87 | GSK3B (0.68) | GSK3BCDK2CCNE1 | |
| SCHEMBL13121486 | 0.87 | GSK3B (0.68) | GSK3BCDK2CCNE1 | |
| SCHEMBL13119031 | 0.87 | GSK3B (0.74) | GSK3BCDK2CCNE1 | |
| SCHEMBL13121479 | 0.86 | GSK3B (0.73) | GSK3BCDK2CCNE1 | |
| SCHEMBL13118921 | 0.86 | GSK3B (0.66) | GSK3BCDK2CCNE1 | |
| SCHEMBL12952866 | 0.86 | GSK3B (0.78) | GSK3BCDK2CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720882-B1 | PYRAZOLOPYRIMIDINE-DERIVATIVES AS CYCLIN DEPENDENT KINASE INHIBITORS | SCHERING CORP (US) | 2011-01-05 | — | — | EP | disclosed |