Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 13/20 | 0.55 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 4/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12953901 | 0.91 | GSK3B (0.69) | GSK3BCDK2CCNE1 | |
| SCHEMBL13304983 | 0.86 | GSK3B (0.61) | GSK3BCHEK1CDK2CCNE1 | |
| SCHEMBL14545867 | 0.83 | GSK3B (0.59) | GSK3BCHEK1CDK2CCNE1 | |
| SCHEMBL12954377 | 0.83 | GSK3B (0.55) | GSK3BCHEK1CDK2CCNE1 | |
| SCHEMBL13118885 | 0.83 | GSK3B (0.69) | GSK3BCDK2CCNE1 | |
| SCHEMBL14418926 | 0.82 | GSK3B (0.59) | GSK3BCHEK1CDK2CCNE1 | |
| SCHEMBL14545244 | 0.82 | GSK3B (0.55) | GSK3BCHEK1CDK2CCNE1 | |
| SCHEMBL14418649 | 0.81 | GSK3B (0.53) | GSK3BCHEK1CDK2CCNE1 | |
| SCHEMBL13288736 | 0.81 | GSK3B (0.53) | GSK3BCHEK1CDK2CCNE1 | |
| SCHEMBL12953703 | 0.81 | GSK3B (0.55) | GSK3BCHEK1CDK2CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007044449-A2 | NOVEL PYRAZOLOPYRIMIDINES AS CYCLIN DEPENDENT KINASE INHIBITORS | SCHERING CORPORATION (US) | 2007-04-19 | — | — | WO | disclosed |