Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 14/20 | 0.78 |
| ▸ | CDK2 | P24941 | 6/20 | 0.64 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.57 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13122120 | 0.89 | GSK3B (0.72) | GSK3BCDK2CCNE1CHEK1 | |
| SCHEMBL13305208 | 0.89 | GSK3B (0.85) | GSK3BCDK2CCNE1 | |
| SCHEMBL12953591 | 0.89 | GSK3B (0.98) | GSK3BCDK2CCNE1 | |
| SCHEMBL13122203 | 0.89 | GSK3B (0.80) | GSK3BCDK2CCNE1 | |
| SCHEMBL12954242 | 0.89 | GSK3B (0.77) | GSK3BCDK2CCNE1 | |
| SCHEMBL13122124 | 0.88 | GSK3B (0.71) | GSK3BCDK2CCNE1CHEK1 | |
| SCHEMBL13122126 | 0.88 | GSK3B (0.73) | GSK3BCDK2CCNE1 | |
| SCHEMBL12952884 | 0.88 | GSK3B (0.73) | GSK3BCDK2CCNE1 | |
| SCHEMBL12952848 | 0.88 | GSK3B (1.00) | GSK3BCDK2CCNE1 | |
| SCHEMBL13122207 | 0.88 | GSK3B (0.82) | GSK3BCDK2CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720882-B1 | PYRAZOLOPYRIMIDINE-DERIVATIVES AS CYCLIN DEPENDENT KINASE INHIBITORS | SCHERING CORP (US) | 2011-01-05 | — | — | EP | disclosed |