Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 15/20 | 0.85 |
| ▸ | CDK2 | P24941 | 6/20 | 0.70 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12953729 | 0.92 | GSK3B (1.00) | GSK3BCDK2CCNE1 | |
| SCHEMBL12953591 | 0.90 | GSK3B (0.98) | GSK3BCDK2CCNE1 | |
| SCHEMBL13118777 | 0.90 | GSK3B (0.81) | GSK3BCDK2CCNE1 | |
| SCHEMBL12952848 | 0.89 | GSK3B (1.00) | GSK3BCDK2CCNE1 | |
| SCHEMBL12954238 | 0.89 | GSK3B (0.78) | GSK3BCDK2CCNE1 | |
| SCHEMBL13122098 | 0.89 | GSK3B (0.84) | GSK3BCDK2CCNE1 | |
| SCHEMBL13122091 | 0.89 | GSK3B (0.82) | GSK3BCDK2CCNE1 | |
| SCHEMBL14545270 | 0.89 | GSK3B (0.67) | GSK3BCDK2CCNE1 | |
| SCHEMBL12952894 | 0.88 | GSK3B (0.78) | GSK3BCDK2CCNE1 | |
| SCHEMBL14598589 | 0.88 | GSK3B (0.78) | GSK3BCDK2CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537116-B1 | PYRAZOLOPYRIMIDINES SUITABLE FOR THE TREATMENT OF CANCER DISEASES | SCHERING CORP (US) | 2010-06-02 | — | — | EP | disclosed |