SCHEMBL12954591

SCHEMBL12954591

C/C=C/Cc1ccccc1F

nearest known ligand 0.56

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 4/20 0.56
IDO1 P14902 2/20 0.47
AOC3 Q16853 1/20 0.46
LMNA P02545 1/20 0.38
ALDH1A1 P00352 5/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
MAOB P27338 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.36
MAPT P10636 1/20 0.36
PKM P14618 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11456607 1.00 TAAR1 (0.56) TAAR1IDO1AOC3LMNAALDH1A1
SCHEMBL7559119 0.84 TAAR1 (0.41) TAAR1IDO1MAOB
SCHEMBL9419298 0.83 TAAR1 (0.42) TAAR1IDO1AOC3MAOB
SCHEMBL5316677 0.82 TAAR1 (0.48) TAAR1IDO1AOC3LMNAALDH1A1
SCHEMBL29140373 0.78 TAAR1 (0.50) TAAR1IDO1AOC3LMNAALDH1A1
SCHEMBL28743508 0.78 TAAR1 (0.50) TAAR1IDO1AOC3LMNAALDH1A1
SCHEMBL9593292 0.78 TAAR1 (0.50) TAAR1IDO1AOC3LMNAALDH1A1
SCHEMBL20985487 0.77 TAAR1 (0.54) TAAR1IDO1AOC3LMNAALDH1A1
SCHEMBL23897100 0.76 CYP3A4 (0.39) TAAR1ALDH1A1MEN1KMT2AL3MBTL1
SCHEMBL1276610 0.76 TAAR1 (0.56) TAAR1LMNAALDH1A1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111419830-B Phenylalkylcarbamate compounds for use in the prevention or treatment of epilepsy and epileptic related syndromes 比皮艾思药物研发有限公司 2024-01-30 CN disclosed
CN-115996905-A Phenylalkyl carbamate compounds for use in preventing or treating neurodegenerative diseases 生物药品解决方案有限公司 2023-04-21 CN disclosed
CN-111419830-A Phenylalkylcarbamate compounds for use in the prevention or treatment of epilepsy and epilepsy-related syndromes 比皮艾思药物研发有限公司 2020-07-17 CN disclosed
EP-2968211-A1 PHENYL ALKYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING EPILEPSY OR EPILEPSY-RELATED SYNDROME Bio-Pharm Solutions Co., Ltd. (KR) 2016-01-20 EP disclosed
CN-105209027-A Phenylalkylcarbamate compounds for use in the prevention or treatment of epilepsy and epilepsy-related syndromes BIO PHARM SOLUTIONS CO LTD 2015-12-30 CN disclosed
EP-2797881-A1 Phenyl alkyl carbamate derivative compound and pharmaceutical composition containing the same Bio-Pharm Solutions Co., Ltd. (KR) 2014-11-05 EP disclosed
WO-2014142519-A1 PHENYL ALKYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING EPILEPSY OR EPILEPSY-RELATED SYNDROME BIO-PHARM SOLUTIONS CO., LTD. (KR) 2014-09-18 WO disclosed
WO-2013100566-A1 Phenyl alkyl carbamate derivative compound and pharmaceutical composition containing the same BIO-PHARM SOLUTIONS CO., LTD. (KR) 2013-07-04 WO disclosed
EP-2272832-A1 PHENYLPROPIONIC ACID DERIVATIVE AND USE THEREOF Asahi Kasei Pharma Corporation (JP) 2011-01-12 EP disclosed