Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11456607 | 0.82 | TAAR1 (0.56) | TAAR1IDO1AOC3LMNAKMT2A | |
| SCHEMBL12954591 | 0.82 | TAAR1 (0.56) | TAAR1IDO1AOC3LMNAKMT2A | |
| SCHEMBL12473708 | 0.78 | TAAR1 (0.50) | TAAR1IDO1AOC3LMNAKMT2A | |
| SCHEMBL575057 | 0.78 | TAAR1 (0.50) | TAAR1IDO1AOC3LMNAKMT2A | |
| SCHEMBL436798 | 0.77 | TAAR1 (0.56) | TAAR1IDO1AOC3LMNAKMT2A | |
| SCHEMBL3634562 | 0.76 | TAAR1 (0.48) | TAAR1IDO1AOC3LMNAKMT2A | |
| SCHEMBL248425 | 0.76 | TAAR1 (0.48) | TAAR1IDO1AOC3LMNAKMT2A | |
| SCHEMBL30079047 | 0.76 | TAAR1 (0.48) | TAAR1IDO1AOC3LMNAKMT2A | |
| SCHEMBL20985487 | 0.76 | TAAR1 (0.54) | TAAR1IDO1AOC3LMNAKMT2A | |
| SCHEMBL21633667 | 0.76 | TAAR1 (0.48) | TAAR1IDO1AOC3LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013139929-A1 | NOVEL MEANS AND METHODS FOR TREATING DISEASES OF THE CENTRAL NERVOUS SYSTEM, METABOLIC AND CARDIAC DISEASES AND AGING | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2013-09-26 | — | — | WO | claimed |
| CN-103119031-A | Substituted amide compounds | ASTELLAS PHARMA INC | 2013-05-22 | — | — | CN | claimed |
| CN-103119031-B | Substituted amide compounds | ASTELLAS PHARMA INC | 2015-01-14 | — | — | CN | disclosed |
| CN-103929965-A | Method of treatment | GLAXOSMITHKLINE LLC | 2014-07-16 | — | — | CN | disclosed |
| CN-103732065-A | Benzofuran compounds for the treatment of hepatitis c virus infections | GLAXO GROUP LTD | 2014-04-16 | — | — | CN | disclosed |
| WO-2013139929-A1 | NOVEL MEANS AND METHODS FOR TREATING DISEASES OF THE CENTRAL NERVOUS SYSTEM, METABOLIC AND CARDIAC DISEASES AND AGING | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2013-09-26 | — | — | WO | disclosed |
| CN-103119031-A | Substituted amide compounds | ASTELLAS PHARMA INC | 2013-05-22 | — | — | CN | disclosed |
| WO-2012163959-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2012-12-06 | — | — | WO | disclosed |
| CN-102134214-A | Isoindolone compounds and their use as metabotropic glutamate receptor potentiators | ASTRAZENECA SWEDEN AB | 2011-07-27 | — | — | CN | disclosed |
| CN-101039907-B | Isoindolone compounds and their use as metabotropic glutamate receptor potentiators | ASTRAZENECA AB | 2011-02-23 | — | — | CN | disclosed |
| CN-101039907-A | Isoindolone compounds and their use as metabotropic glutamate receptor potentiators | ASTRAZENECA AB (SE) | 2007-09-19 | — | — | CN | disclosed |
| WO-2007069053-A1 | BENZIMIDAZOLE ANTAGONISTS OF THE H-3 RECEPTOR | PFIZER PRODUCTS INC. (US) | 2007-06-21 | — | — | WO | disclosed |
| CN-1950089-A | Morpholine compounds | PFIZER LTD (US) | 2007-04-18 | — | — | CN | disclosed |
| EP-1334976-B1 | Novel phosphine compound, transition metal complex containing said compound as ligand and asymetric synthesis catalyst containing said complex | TAKASAGO PERFUMERY CO LTD (JP) | 2006-03-08 | — | — | EP | disclosed |
| EP-1334976-A1 | Novel phosphine compound, transition metal complex containing said compound as ligand and asymetric synthesis catalyst containing said complex | Takasago International Corporation (JP) | 2003-08-13 | — | — | EP | disclosed |
| US-5192767-A | Nonphytotoxic | BASF AKTIENGESELLSCHAFT (DE) | 1993-03-09 | — | — | US | disclosed |
| EP-0311907-A2 | 3-Substituted pyridines and fungicides containing them | BASF Aktiengesellschaft (DE) | 1989-04-19 | — | — | EP | disclosed |