Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 8/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | PTPRA | P18433 | 1/20 | 0.58 |
| ▸ | PTPRB | P23467 | 1/20 | 0.58 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.48 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14134824 | 0.92 | CYP1A2 (0.59) | CYP1A2CYP2C9HIF1ATSHRCYP2C19 | |
| SCHEMBL12954983 | 0.83 | CYP1A2 (0.58) | CYP1A2CYP2C9HIF1ATSHRCYP2C19 | |
| SCHEMBL13474933 | 0.80 | CYP1A2 (0.53) | CYP1A2CYP2C9HIF1ATSHRCYP2C19 | |
| SCHEMBL13659235 | 0.74 | CYP1A2 (1.00) | CYP1A2CYP2C9HIF1ATSHRCYP2C19 | |
| SCHEMBL15424238 | 0.74 | CYP1A2 (1.00) | CYP1A2CYP2C9HIF1ATSHRCYP2C19 | |
| SCHEMBL13474913 | 0.74 | CYP1A2 (0.51) | CYP1A2CYP2C9HIF1ATSHRCYP2C19 | |
| SCHEMBL12955461 | 0.71 | CYP1A2 (0.52) | CYP1A2CYP2C9HIF1ATSHRCYP2C19 | |
| SCHEMBL15113020 | 0.70 | CTRB1 (0.70) | CYP1A2CYP2C9HIF1ATSHRCYP2C19 | |
| SCHEMBL14907080 | 0.70 | CYP1A2 (0.78) | CYP1A2CYP2C9HIF1ATSHRCYP2C19 | |
| SCHEMBL4954382 | 0.69 | CYP1A2 (0.57) | CYP1A2CYP2C9HIF1ATSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2142011-B1 | METHOD FOR MODULATING THE TASTE OF MATERIAL COMPISITIONS CONTAINING AT LEAST ONE HIGH INTENSITY SWEETENER (HIS) | BRAIN BIOTECHNOLOGY RES & INFORMATION NETWORK AG (DE) | 2011-01-12 | — | — | EP | disclosed |