Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 7/20 | 0.73 |
| ▸ | PGR | P06401 | 1/20 | 0.67 |
| ▸ | GLUL | P15104 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12956461 | 1.00 | NR3C1 (0.73) | NR3C1PGRGLUL | |
| SCHEMBL13581548 | 1.00 | NR3C1 (0.73) | NR3C1PGRGLUL | |
| SCHEMBL12956239 | 0.94 | NR3C1 (0.72) | NR3C1 | |
| SCHEMBL12956245 | 0.94 | NR3C1 (0.72) | NR3C1 | |
| SCHEMBL12956584 | 0.92 | NR3C1 (0.76) | NR3C1GLUL | |
| SCHEMBL12956583 | 0.92 | NR3C1 (0.76) | NR3C1GLUL | |
| SCHEMBL12956623 | 0.88 | NR3C1 (0.70) | NR3C1 | |
| SCHEMBL12956625 | 0.88 | NR3C1 (0.70) | NR3C1 | |
| SCHEMBL14261416 | 0.87 | NR3C1 (0.71) | NR3C1GLUL | |
| SCHEMBL12956267 | 0.87 | NR3C1 (0.71) | NR3C1GLUL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1496892-B1 | 1H-BENZO(F)INDAZOL-5-YL DERIVATIVES AS SELECTIVE GLUCOCORTICOID RECEPTOR MODULATORS | MERCK SHARP & DOHME (US) | 2011-01-26 | — | — | EP | disclosed |