Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21894227 | 0.87 | TAAR1 (0.49) | NPC1RAB9ANPSR1MEN1KMT2A | |
| SCHEMBL13091213 | 0.83 | SRC (0.44) | NPC1RAB9ANPSR1MEN1KMT2A | |
| SCHEMBL27927872 | 0.80 | NPSR1 (0.48) | NPC1RAB9ANPSR1MEN1KMT2A | |
| SCHEMBL2441467 | 0.79 | NOTUM (0.48) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL8186371 | 0.79 | NPSR1 (0.47) | NPC1RAB9ANPSR1MEN1KMT2A | |
| SCHEMBL324789 | 0.79 | NPSR1 (0.68) | NPC1RAB9ANPSR1MEN1KMT2A | |
| SCHEMBL31689801 | 0.79 | NPSR1 (0.68) | NPC1RAB9ANPSR1MEN1KMT2A | |
| SCHEMBL2441173 | 0.77 | GPR17 (0.38) | NPSR1MEN1KMT2ATGM2ALDH1A1 | |
| SCHEMBL12226963 | 0.77 | NPSR1 (0.46) | NPC1RAB9ANPSR1MEN1KMT2A | |
| SCHEMBL22522189 | 0.75 | FFAR1 (0.50) | TGM2ALDH1A1L3MBTL1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1869025-B1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENES FOR TREATMENT OF MENTAL DISORDERS | OTSUKA PHARMA CO LTD (JP) | 2011-01-26 | — | — | EP | disclosed |