Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 20/20 | 0.53 |
| ▸ | PPIB | P23284 | 5/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | PPIF | P30405 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.46 |
| ▸ | ABCC2 | Q92887 | 2/20 | 0.46 |
| ▸ | SLCO1B3 | Q9NPD5 | 2/20 | 0.46 |
| ▸ | SLCO1B1 | Q9Y6L6 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9880086 | 0.86 | PPIA (0.56) | PPIAPPIBCYP3A4CYP2C9PPIF | |
| SCHEMBL9880088 | 0.85 | PPIA (0.57) | PPIAPPIBCYP3A4CYP2C9PPIF | |
| SCHEMBL9880084 | 0.85 | PPIA (0.63) | PPIAPPIBCYP3A4CYP2C9PPIF | |
| SCHEMBL9976361 | 0.80 | FKBP1B (0.53) | PPIAPPIBCYP3A4CYP2C9PPIF | |
| SCHEMBL15462821 | 0.75 | PPIA (0.89) | PPIAPPIBCYP3A4CYP2C9PPIF | |
| SCHEMBL9976362 | 0.75 | FKBP1B (0.46) | PPIAPPIBCYP3A4CYP2C9PPIF | |
| SCHEMBL9976370 | 0.74 | FKBP1B (0.46) | PPIAPPIBPPIFABCB11ABCB1 | |
| SCHEMBL9976371 | 0.73 | ABCB1 (0.54) | PPIAPPIBCYP3A4CYP2C9PPIF | |
| SCHEMBL9976369 | 0.72 | ABCB1 (0.52) | PPIAPPIBCYP3A4CYP2C9PPIF | |
| SCHEMBL9976364 | 0.71 | FKBP1B (0.46) | PPIAPPIBCYP3A4CYP2C9PPIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9119853-B2 | Sanglifehrin based compounds | NEUROVIVE PHARMACEUTICAL AB (SE) | 2015-09-01 | — | — | US | disclosed |
| US-9090657-B2 | Compound and methods for its production | NEUROVIVE PHARMACEUTICAL AB (SE) | 2015-07-28 | — | — | US | disclosed |
| US-20120295841-A1 | Sanglifehrin Based Compounds | Abliva Ab (SE) | 2012-11-22 | — | — | US | disclosed |
| US-20120251581-A1 | Novel Compound and Methods for its Production | Abliva Ab (SE) | 2012-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295841-A1 | Sanglifehrin Based Compounds | HSP90B1, HSPH1, HSP90AB2P | PPIA 22/4885PPIB 14/4885CYP3A4 2362/4885 |
| US-20120251581-A1 | Novel Compound and Methods for its Production | EIF2AK2, HAVCR2, CYP51A1 | PPIA 238/4885PPIB 226/4885CYP3A4 82/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.