Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 20/20 | 0.57 |
| ▸ | PPIB | P23284 | 9/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | PPIF | P30405 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9880084 | 0.95 | PPIA (0.63) | PPIAPPIBCYP3A4CYP2C9PPIF | |
| SCHEMBL9880086 | 0.90 | PPIA (0.56) | PPIAPPIBCYP3A4CYP2C9PPIF | |
| SCHEMBL12958868 | 0.85 | PPIA (0.53) | PPIAPPIBCYP3A4CYP2C9PPIF | |
| SCHEMBL9976361 | 0.81 | FKBP1B (0.53) | PPIAPPIBCYP3A4CYP2C9PPIF | |
| SCHEMBL9976362 | 0.77 | FKBP1B (0.46) | PPIAPPIBCYP3A4CYP2C9PPIF | |
| SCHEMBL15183870 | 0.75 | PPIA (0.92) | PPIAPPIBCYP3A4CYP2C9PPIF | |
| SCHEMBL9976370 | 0.75 | FKBP1B (0.46) | PPIAPPIBPPIF | |
| SCHEMBL9976371 | 0.74 | ABCB1 (0.54) | PPIAPPIBCYP3A4CYP2C9PPIF | |
| SCHEMBL15183869 | 0.74 | PPIA (0.88) | PPIAPPIB | |
| SCHEMBL12361652 | 0.73 | PPIB (0.60) | PPIAPPIBPPIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9175042-B2 | Cyclosporin analogs | ALLERGAN, INC. (US) | 2015-11-03 | — | — | US | disclosed |
| US-20120135939-A1 | Cyclosporin Analogs | ALLERGAN, INC. (US) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135939-A1 | Cyclosporin Analogs | CHP1, TSLP, PPP3R1 | PPIA 202/4885PPIB 149/4885CYP3A4 864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.