Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 9/20 | 0.50 |
| ▸ | SYK | P43405 | 8/20 | 0.49 |
| ▸ | AURKA | O14965 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1068181 | 0.93 | BTK (0.58) | BTKSYKAURKA | |
| SCHEMBL12637988 | 0.93 | BTK (0.58) | BTKSYKAURKA | |
| SCHEMBL1068183 | 0.93 | BTK (0.58) | BTKSYKAURKA | |
| SCHEMBL16712265 | 0.85 | BTK (0.41) | BTKSYKAURKA | |
| SCHEMBL16712263 | 0.85 | BTK (0.41) | BTKSYKAURKA | |
| SCHEMBL1066572 | 0.82 | BTK (0.61) | BTKSYKAURKA | |
| SCHEMBL1069949 | 0.82 | BTK (0.55) | BTKSYKAURKA | |
| SCHEMBL1069951 | 0.82 | BTK (0.55) | BTKSYKAURKA | |
| SCHEMBL12638024 | 0.82 | BTK (0.55) | BTKSYKAURKA | |
| SCHEMBL12962408 | 0.82 | BTK (0.60) | BTKSYKAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2270200-A2 | Kinase inhibitors, and methods of using and identifying kinase inhibitors | CGI Pharmaceuticals, Inc. (US) | 2011-01-05 | — | — | EP | disclosed |